| Identification | Back Directory | [Name]
DEPHOSTATIN | [CAS]
151606-30-3 | [Synonyms]
DEPHOSTATIN
2-(N-METHYL-N-NITROSO)HYDROQUINONE
2-(methylnitrosoamino)-4-benzenediol
2-(METHYLNITROSOAMINO)-1,4-BENZENEDIOL
2,5-DIHYDROXY-N-METHYL-N-NITROSOANILINE
1,4-DIHYDROXY-N-METHYL-N-NITROSOANILINE
1,4-Benzenediol, 2-(methylnitrosoamino)-
Dephostatin - CAS 151606-30-3 - Calbiochem
1,4-Dihydroxy-N-methyl-N-nitrosoaniline, 2-(Methylnitrosoamino)-1,4-benzenediol, 2-(N-methyl-N-nitroso)hydroquinone | [Molecular Formula]
C7H8N2O3 | [MDL Number]
MFCD00467665 | [MOL File]
151606-30-3.mol | [Molecular Weight]
168.15 |
| Chemical Properties | Back Directory | [Boiling point ]
424.1±45.0 °C(Predicted) | [density ]
1.36±0.1 g/cm3(Predicted) | [storage temp. ]
−20°C | [solubility ]
DMSO: 22 mg/mL, soluble | [form ]
solid | [pka]
9.23±0.43(Predicted) | [color ]
light yellow |
| Hazard Information | Back Directory | [Uses]
Dephostatin is a competitive protein tyrosine phosphatase (PTP) inhibitor that can be isolated from Streptomyces spp., with activity in the micromolar range[1]. | [References]
[1] Ferreira CV, et al. Natural compounds as a source of protein tyrosine phosphatase inhibitors: application to the rational design of small-molecule derivatives. Biochimie. 2006 Dec;88(12):1859-73. DOI:10.1016/j.biochi.2006.08.007 |
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