| Identification | Back Directory | [Name]
2-PHENYLMELATONIN | [CAS]
151889-03-1 | [Synonyms]
2-PHENYLMELATONIN
Melatonin Impurity 11
Melatonin 2-Phenyl Impurity
N-[2-(5-METHOXY-2-PHENYLINDOL-3-YL)ETHYL]ACETAMIDE
N-[2-(5-methoxy-2-phenyl-1H-indol-3-yl)ethyl]acetamide
Acetamide, N-[2-(5-methoxy-2-phenyl-1H-indol-3-yl)ethyl]- | [Molecular Formula]
C19H20N2O2 | [MDL Number]
MFCD00673896 | [MOL File]
151889-03-1.mol | [Molecular Weight]
308.37 |
| Chemical Properties | Back Directory | [storage temp. ]
Desiccate at +4°C | [solubility ]
Soluble to 100 mM in ethanol and to 100 mM in DMSO | [form ]
Powder | [color ]
Off-white to yellow |
| Hazard Information | Back Directory | [Uses]
2-Phenylmelatonin is a melatonin receptor binder with mixed agonist/antagonist activity. | [Definition]
ChEBI: N-[2-(5-methoxy-2-phenyl-1H-indol-3-yl)ethyl]acetamide is a phenylindole. | [Synthesis Reference(s)]
Journal of Medicinal Chemistry, 38, p. 1132, 1995 DOI: 10.1021/jm00007a010 | [Biological Activity]
Highly potent melatonin agonist; displays higher affinity and greater potency than melatonin itself. The EC 50 values for G protein activation in MT 1 and MT 2 -transfected cells are 65 and 58 pM respectively. | [storage]
Desiccate at +4°C |
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