| Identification | Back Directory | [Name]
MYRISTOYL-ARG-LYS-ARG-THR-LEU-ARG-ARG-LEU-OH | [CAS]
152246-40-7 | [Synonyms]
N-M-RKRTLRRL
MYR-N-RKRTLRRL-OH
MYR-EGF-R (651-658)
Myristoyl-RKRTLRRL-OH
EGF Receptor (651-658), myristoylated
N-MYR-ARG-LYS-ARG-THR-LEU-ARG-ARG-LEU
EGF-R FRAGMENT 651-658, MYRISTOYLATED
MYRISTOYLATED EGF-R FRAGMENT (651-658)
MYR-ARG-LYS-ARG-THR-LEU-ARG-ARG-LEU-OH
MYRISTOYL-ARG-LYS-ARG-THR-LEU-ARG-ARG-LEU
MYRISTOYL-ARG-LYS-ARG-THR-LEU-ARG-ARG-LEU-OH
EGF RECEPTOR (HUMAN) (651-658) (N-MYRISTOYLATED)
MYRISTOYLATED EPIDERMAL GROWTH FACTOR-R (651-658)
MYRISTOYLATED EGF-R FRAGMENT (651-658), PKC INHIBITOR
MYRISTOYLATED EPIDERMAL GROWTH FACTOR-R (651-658) SYNTHETIC
EPIDERMAL GROWTH FACTOR RECEPTOR, FRAGMENT 651-658 MYRISTOYLATED
PROTEIN KINASE C INHIBITOR, EGF-R FRAGMENT 651-658, MYRISTOYLATED
EPIDERMAL GROWTH FACTOR RECEPTOR (HUMAN) (651-658) (N-MYRISTOYLATED)
L-Leucine, N2-(1-oxotetradecyl)-L-arginyl-L-lysyl-L-arginyl-L-threonyl-L-leucyl-L-arginyl-L-arginyl- | [Molecular Formula]
C60H117N21O11 | [MDL Number]
MFCD00238306 | [MOL File]
152246-40-7.mol | [Molecular Weight]
1308.71 |
| Hazard Information | Back Directory | [Uses]
N-myristoyl-RKRTLRRL inhibits binding of PKC substrates. N-myristoyl-RKRTLRRL inhibits Ca2+- and phosphatidylserine (PS)-dependent histone phosphorylation with IC50 of 5 μM. histone phosphorylation with IC50 of 80 μM[1][2]. | [References]
[1] David K Crockett, et al. Identification of proteins from formalin-fixed paraffin-embedded cells by LC-MS/MS. Lab Invest. 2005 Nov;85(11):1405-15. DOI:10.1038/labinvest.3700343
[2] C A O'Brian, et al. A novel N-myristylated synthetic octapeptide inhibits protein kinase C activity and partially reverses murine fibrosarcoma cell resistance to Adriamycin. Invest New Drugs. 1991 May;9(2):169-79. DOI:10.1007/BF00175084 |
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| Company Name: |
Combio (Suzhou) Ltd.
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| Telephone: |
17751201929; 17751201929 |
| Website: |
http://www.combiosz.com/ |
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