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153012-37-4

153012-37-4 Structure

153012-37-4 Structure
IdentificationBack Directory
[Name]

[6R-[6alpha,7beta(Z)]]-3-[[(Aminocarbonyl)oxy]methyl]-7-[[2-[2-[[(1,1-dimethylethoxy)carbonyl]amino]-4-thiazolyl]-1-oxo-2-pentenyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid compd. with N-(1-methylethyl)-2-propanamine
[CAS]

153012-37-4
[Synonyms]

BPCM
BCN、BPCM
Boc-Cefcapene
Boc-Cefcapene/BCN
Boc-Cefcapene.DIPA
Cefcapene Impurity 8
Cefcapene InterMediate
Intermediate of Cefcapene
[6R-[6alpha,7beta(Z)]]-3-[[(Amin
Cephalosporin diisopropylamine salt
N-Boc Cefcapene N,N-DiisopropylaMine
precursor of cefcapene diisopropylanmine
Precursor of cefcapene diisopropylanmine salt
[6R-[6alpha,7beta(Z)]]-3-[[(Aminocarbonyl)oxy]methyl]-7-[[2-[2-[[(1,1-di
(6R,7R)-7-[(Z)-2-(2-t-Butoxycarbonylaminothiazol-4-yl)pent-2-enoylamino]-3-carbamoyloxy -methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid diisopropylamine salt
(6R,7R)-7-[[(Z)-2-(2-t-Butoxycarbonylaminothiazol-4-yl)-2-pentenoyl]amino]-3-aminocarbonyl-oxymethyl-8-oxo-5-thia-1-azabicylo[4.2.0]oct-2-ene-2-carboxylic acid diisopropylamine salt
diisopropylamine 7-((2-(2-(2-(tert-butoxy)-2-oxoethyl)thiazol-4-yl)-1-oxidopent-2-en-1-ylidene)amino)-3-((iminooxidomethoxy)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
[6R-[6alpha,7beta(Z)]]-3-[[(Aminocarbonyl)oxy]methyl]-7-[[2-[2-[[(1,1-dimethylethoxy)carbonyl]amino]-4-thiazolyl]-1-oxo-2-pentenyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid compd. with N-(1-met
[6R-[6alpha,7beta(Z)]]-3-[[(Aminocarbonyl)oxy]methyl]-7-[[2-[2-[[(1,1-dimethylethoxy)carbonyl]amino]-4-thiazolyl]-1-oxo-2-pentenyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid compd. with N-(1-methylethyl)-2-propanamine
[6R-[6alpha,7beta(Z)]]-3-[[(Aminocarbonyl)oxy]methyl]-7-[[2-[2-[[(1,1-dimethylethoxy)carbonyl]amino]-4-thiazolyl]-1-oxChemicalbooko-2-pentenyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacidcompd.withN-(1-methylethyl)-2-propanamine USP/EP/BP
[EINECS(EC#)]

604-880-2
[Molecular Formula]

C29H43N5O8S2
[MDL Number]

MFCD31382339
[MOL File]

153012-37-4.mol
[Molecular Weight]

653.81
Questions And AnswerBack Directory
[Preparation]

Precursor of cefcapene diisopropylanmine salt (BCN) is an important intermediate in the synthesis of cefcardine hydrochloride. Starting with 7-aminocephalosporanic acid, it undergoes hydrolysis to yield 3-deacetyl-7-aminocephalosporanic acid, which is then reacted with (Z)-2-(2-tert-butoxycarbonylaminothiazol-4-yl)-2-pentenoic acid and diisopropylamine to obtain Precursor of cefcapene diisopropylanmine salt. The overall yield is over 70%, and the purity is over 98%.

Chemical PropertiesBack Directory
[InChIKey]

IAVQLVKSVQCUFH-SQQJSBOGSA-N
Safety DataBack Directory
[Symbol(GHS) ]

Health Hazard (GHS08)
GHS08
[Signal word ]

Danger
[Hazard statements ]

H317-H334
[Precautionary statements ]

P261-P285-P304+P341-P342+P311-P501-P261-P272-P280-P302+P352-P333+P313-P321-P363-P501
Hazard InformationBack Directory
[Description]

The precursor of Boc-Cefcapene(BCN) is a key intermediate in the synthesis of Cefcapene. Cefcapene is a fourth generation cephalosporin antibiotic, which introduces protective groups on its side chain amino group and the carboxyl group of the cephalosporin nucleus to obtain the precursor of Boc-Cefcapene(BCN). After modification of the BCN, various Cefcapene drugs can be obtained.
[Chemical Properties]

Yellowish crystalline powder.
[Uses]

N-Boc Cefcapene N,N-Diisopropylamine is a precursor of Cefcapene N,N-Diisopropylamine.
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