| Identification | Back Directory | [Name]
CLOPYRALID METHYL ESTER | [CAS]
1532-24-7 | [Synonyms]
Clopyralid-methyl
Clopyralid-methyl [iso]
CLOPYRALID METHYL ESTER
Clopyralid acid, methyl ester
Clopyralid methyl ester Solution
Methyl 3,6-dichloro-2-pyridinecarboxylate
Clopyralid methyl ester @100 μg/mL in Methanol
2-Pyridinecarboxylic acid, 3,6-dichloro-, Methyl ester
Methyl 3,6-dichloropicolinate, 3,6-Dichloro-2-(methoxycarbonyl)pyridine | [Molecular Formula]
C7H5Cl2NO2 | [MDL Number]
MFCD00186642 | [MOL File]
1532-24-7.mol | [Molecular Weight]
206.03 |
| Chemical Properties | Back Directory | [Melting point ]
53-54 °C | [Boiling point ]
296.0±35.0 °C(Predicted) | [density ]
1.426±0.06 g/cm3(Predicted) | [storage temp. ]
under inert gas (nitrogen or Argon) at 2-8°C | [solubility ]
Chloroform (Slightly), DMSO (Slightly) | [form ]
powder | [pka]
-3.63±0.10(Predicted) | [color ]
White |
| Hazard Information | Back Directory | [Description]
Clopyralid methyl is a selective herbicide used to control weeds in turf. It is moderately persistent in the environment and, based on its physico-chemical properties, it has high potential to leach to groundwater. Clopyralid methyl tends to be low to moderately toxic to fauna and flora. It has a low mammalian toxicity as a skin, eye and respiratory irritant. | [Production Methods]
Clopyralid-methyl is produced through an industrial process that mirrors the broader chemistry used for pyridine-carboxylate herbicides, with manufacturers focusing on efficient assembly of the chlorinated pyridine ring and clean esterification to achieve the required purity. Commercial routes begin with production of the 3,6-dichloropicolinic acid core, typically via chlorination and oxidation steps applied to a substituted pyridine precursor, followed by purification to remove regioisomeric and over-chlorinated by-products. This acid is then activated, often as an acid chloride or via mixed-anhydride chemistry, and reacted with methanol or a protected methanol derivative under controlled, anhydrous conditions to form the methyl ester. Downstream operations include solvent exchange, crystallisation, and multi-stage filtration to meet agrochemical specifications and minimise residual acid, chlorinated impurities, and solvent traces. | [Mechanism of action]
Selective, systemic, absorbed through leaves and roots. Synthetic auxin. | [Pesticide Type]
Herbicide |
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