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153314-49-9

153314-49-9 Structure

153314-49-9 Structure
IdentificationBack Directory
[Name]

L-Alaninamide, N-acetyl-3-(1-naphthalenyl)-L-alanyl-L-valyl-(3S,4S)-4-amino-3-hydroxy-6-methylheptanoyl-(2S)-2-aminobutanoyl-3-(1-naphthalenyl)-
[CAS]

153314-49-9
[Synonyms]

LP130
LP-130
LP 130
L-Alaninamide, N-acetyl-3-(1-naphthalenyl)-L-alanyl-L-valyl-(3S,4S)-4-amino-3-hydroxy-6-methylheptanoyl-(2S)-2-aminobutanoyl-3-(1-naphthalenyl)-
[Molecular Formula]

C45H58N6O7
[MOL File]

153314-49-9.mol
[Molecular Weight]

794.99
Chemical PropertiesBack Directory
[Boiling point ]

1174.0±65.0 °C(Predicted)
[density ]

1.201±0.06 g/cm3(Predicted)
[pka]

13.15±0.46(Predicted)
Hazard InformationBack Directory
[Description]

LP 130 is a retroviral protease inhibitor.
[Uses]

LP-130 is a statin-based inhibitor that is a universal inhibitor with nanomolar inhibitory activity against all tested retroviral proteases. Crystal structure studies of its binding to different retroviral proteases have shown that it can adapt to different active site regions to achieve inhibition.
[References]

[1] Toward a universal inhibitor of retroviral proteases: comparative analysis of the interactions of LP-130 complexed with proteases from HIV-1, FIV, and EIAV
153314-49-9 suppliers list
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Company Name: TargetMol Chemicals Inc.  
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