| Identification | Back Directory | [Name]
THREO-DIHYDROBUPROPION | [CAS]
153365-82-3 | [Synonyms]
Urea,N,N'
-dimethyl-N'
THREO-HYDROBUPROPION
THREO-DIHYDROBUPROPION
threo-Hydroxy Bupropion HCl
-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]-
(R*,R*)-2-(T-BUTYLAMINO)1-(3-CHLOROPHENYL) PROPANOL
(R*,R*)-2-(T-BUTYLAMINO)1-(3-CHLOROPHENYL) PROPANOL MALEATE
Benzenemethanol, 3-chloro-α-[(1R)-1-[(1,1-dimethylethyl)amino]ethyl]-, (αR)-
Threo- hydroxy BupropionQ: What is
Threo- hydroxy Bupropion Q: What is the CAS Number of
Threo- hydroxy Bupropion Q: What is the storage condition of
Threo- hydroxy Bupropion Q: What are the applications of
Threo- hydroxy Bupropion
Rac Threo-Dihydrobupropion HydrochlorideQ: What is
Rac Threo-Dihydrobupropion Hydrochloride Q: What is the CAS Number of
Rac Threo-Dihydrobupropion Hydrochloride Q: What is the storage condition of
Rac Threo-Dihydrobupropion Hydrochloride Q: What are the applications of
Rac Threo-Dihydrobupropion Hydrochloride | [Molecular Formula]
C13H20ClNO | [MDL Number]
MFCD00871183 | [MOL File]
153365-82-3.mol | [Molecular Weight]
241.76 |
| Hazard Information | Back Directory | [Uses]
Threo-dihydrobupropion is a major metabolite of Bupropion, formed via oxidation and reduction exhibit pharmacological activity. Bupropion, a dual dopamine-norepinephrine uptake inhibitor and a nicotine receptor antagonist, is widely used in the management of depression and as a smoking cessation aid[1]. | [References]
[1] Andrea R Masters, et al. Stereoselective method to quantify bupropion and its three major metabolites, hydroxybupropion, erythro-dihydrobupropion, and threo-dihydrobupropion using HPLC-MS/MS. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Mar 15;1015-1016:201-208. DOI:10.1016/j.jchromb.2016.02.018 |
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