| Identification | Back Directory | [Name]
XJ735 | [CAS]
153381-95-4 | [Synonyms]
XJ735
XJ735 TRIFLUOROACETATE SALT
cyclo(ala-arg-gly-asp-3-aminomethylbenzoyl)
CYCLO(-ALA-ARG-GLY-ASP-3-AMINOMETHYLBENZOYL) TFA
CYCLO(ALA-ARG-GLY-ASP-3-AMINOMETHYL-*BENZOYL)TRIFLU
Cyclo(Ala-Arg-Gly-Asp-3-Aminomethylbenzoyl) >=96% (HPLC)
CYCLO(-ALA-ARG-GLY-ASP-3-AMINOMETHYLBENZOYL) TRIFLUOROACETATE SALT
Cyclo[L-alanyl-L-arginylglycyl-L-α-aspartyl-3-(aminomethyl)benzoyl]
3,6,9,12,15-Pentaazabicyclo[15.3.1]heneicosane,cyclic peptide deriv. | [Molecular Formula]
C23H32N8O7 | [MDL Number]
MFCD11046000 | [MOL File]
153381-95-4.mol | [Molecular Weight]
532.55 |
| Chemical Properties | Back Directory | [density ]
1.53±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C | [form ]
powder | [pka]
4.02±0.10(Predicted) | [color ]
white | [Sequence]
Cyclo(Ala-Arg-Gly-Asp-{Oaa}) | [InChIKey]
HRASXYOWQQTBAQ-RCBQFDQVSA-N | [SMILES]
C[C@@H]1NC(=O)c2cccc(CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC1=O)c2 |
| Hazard Information | Back Directory | [Uses]
Cyclo(Ala-Arg-Gly-Asp-Mamb) is a selective RGD peptide antagonist and has the potential for Pulmonary arterial hypertension
Research[1]. | [Biochem/physiol Actions]
Cyclo(Ala-Arg-Gly-Asp-3-Aminomethylbenzoyl) (XJ735) is an RGD containing cyclic peptide (peptidomimetic) used as an antagonist specific to integrin αvβ3. XJ735 is used to study the role of integrin αvβ3 in cell-matrix interactions and processes. | [References]
[1] Liukun Meng et al. Osteopontin plays important roles in pulmonary arterial hypertension induced by systemic-to-pulmonary shunt. FASEB J. 2019 Jun;33(6):7236-7251. DOI:10.1096/fj.201802121RR |
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| Company Name: |
BOC Sciences
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| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
Alabiotech Inc.
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| Tel: |
001-619-354-5251 |
| Website: |
www.alabiotech-e.com |
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