153463-21-9

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153463-21-9 Structure

Identification	Back Directory
[Name] 25,26,26,26,27,27,27-heptafluorocholesterol
[CAS] 153463-21-9
[Synonyms] F7-Cholesterol 25,26,26,26,27,27,27-heptafluorocholesterol 25,26,26,26,27,27,27-HEPTAFLUOROCHOLESTEROL;F7-CHOLESTEROL Cholest-5-en-3-ol, 25,26,26,26,27,27,27-heptafluoro-, (3β)-
[Molecular Formula] C27H39F7O
[MDL Number] MFCD28143665
[MOL File] 153463-21-9.mol
[Molecular Weight] 512.59

Chemical Properties	Back Directory
[Boiling point ] 465.8±40.0 °C(Predicted)
[density ] 1.20±0.1 g/cm3(Predicted)
[storage temp. ] -20°C
[form ] powder
[pka] 15.03±0.70(Predicted)
[EPA Substance Registry System] (3.beta.)-25,26,26,26,27,27,27-Heptafluoro-cholest-5-en-3-ol (153463-21-9)

Hazard Information	Back Directory
[Uses] F7-Cholesterol has been used: in the preparation of liposomes for DNA delivery studies to investigate its rescue functionality in hedgehog signaling in sterol-depleted cells in preparation of monolayers for pressure and area isotherms studies
[General Description] F7-Cholesterol is a fluorinated derivative of cholesterol. It is a cholesterol analog. F7-Cholesterol is useful as helper lipid in conjunction with vectors for DNA transfection.
[Biochem/physiol Actions] F7-Cholesterol has potential biological applications. It has a negative dipole moment. F7-Cholesterol rescues hedgehog signaling in sterol-depleted cells. The molecular orientation and phospholipid interaction of F7-cholesterol is similar to hydrogenated cholesterol.

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