| Identification | Back Directory | [Name]
13-hydroxylupanine | [CAS]
15358-48-2 | [Synonyms]
13-hydroxylupanine
(+)-13α-Hydroxylupanine
(+)-13α-Hydroxylupanine Hydrochloride
(7S,7aβ,9β,14S,14aα)-Dodecahydro-9-hydroxy-7,14-methano-4H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocin-4-one
7,14-Methano-2H,11H-dipyrido[1,2-a:1',2'-e][1,5]diazocin-11-one, dodecahydro-2-hydroxy-, (2S,7S,7aR,14S,14aS)- | [Molecular Formula]
C15H24N2O2 | [MOL File]
15358-48-2.mol | [Molecular Weight]
264.36 |
| Chemical Properties | Back Directory | [Melting point ]
169-170° | [alpha ]
D20 +45.6° (c = 1.49 in ethanol); D20 +65.1° (c = 1.09 in water) | [Boiling point ]
407.59°C (rough estimate) | [density ]
1.0200 (rough estimate) | [refractive index ]
1.5800 (estimate) | [storage temp. ]
-20°C Freezer, Under inert atmosphere | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
14.82±0.20(Predicted) | [color ]
Off-White to Pale Yellow |
| Hazard Information | Back Directory | [Description]
Hydroxylupanine is an alkaloid that has been found in L. lanatus. It is an inhibitor of ganglionic transmission. | [Uses]
(+)-13α-Hydroxylupanine is used in analytical studies for the determination of Lupinus polyphyllus by thin-layer chromatography and fluorescence. | [storage]
Store at -20°C | [References]
[1] ALEXANDRE T. NETO. Quinolizidine alkaloids from Lupinus lanatus[J]. Journal of Molecular Structure, 2011, 1004 1: Pages 174-177. DOI: 10.1016/j.molstruc.2011.07.061
[2] D S PETTERSON. Disposition of lupanine and 13-hydroxylupanine in man.[J]. Xenobiotica, 1994, 24 9: 933-941. DOI: 10.3109/00498259409043291 |
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