| Identification | Back Directory | [Name]
L-Alaninamide, L-tyrosyl-L-valyl-N-[(1S)-2-carboxy-1-formylethyl]- (9CI) | [CAS]
153604-27-4 | [Synonyms]
L-Alaninamide, L-tyrosyl-L-valyl-N-[(1S)-2-carboxy-1-formylethyl]- (9CI) | [Molecular Formula]
C21H30N4O7 | [MOL File]
153604-27-4.mol | [Molecular Weight]
450.49 |
| Chemical Properties | Back Directory | [Boiling point ]
843.5±65.0 °C(Predicted) | [density ]
1.284±0.06 g/cm3(Predicted) | [pka]
4.20±0.10(Predicted) | [Sequence]
Tyr-Val-Ala-Asp-{CHO} |
| Hazard Information | Back Directory | [Uses]
YVAD-CHO is an interleukin-1β converting enzyme (ICE, caspase 1) inhibitor that can partially delay motoneurone death in lesioned facial nerve mice[1]. | [References]
[1] de Bilbao F, Dubois-Dauphin M. Acute application of an interleukin-1 beta-converting enzyme-specific inhibitor delays axotomy-induced motoneurone death. Neuroreport. 1996 Nov 25;7(18):3051-4. DOI:10.1097/00001756-199611250-00051 |
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