| Identification | Back Directory | [Name]
TRIPELENNAMINE HYDROCHLORIDE | [CAS]
154-69-8 | [Synonyms]
ReCovr
Azaron
dehistin
piristin
Ahistamin
pyrinamine
stanzamine
tri-tumine
pyrabenzamine
TRIPELENAMINEHCL
PYRIBENZAMINE HCL
TRIPELENNAMINE HCL
TripelennaMine HCI
Antiallergicum medivet
dehistinmonohydrochloride
pyribenzaminehydrochloride
tripelenaminehydrochloride
TRIPELENNAMINE HYDROCHLORIDE
Chloropyramine Impurity 1 HCl
Tripelennanmine Hydrochloride
pyribenzaminemonohydrochloride
tripelennaminemonohydrochloride
TRIPELENNAMINEHYDROCHLORIDE,USP
TRIPELENNAMINE HYDROCHLORIDE TABLETS
Tripelennamine Hydrochloride (200 mg)
Tripelennamine Hydrochloride Standard
TRIPELENNAMINE HYDROCHLORIDE USP/EP/BP
N-Benzyl-N',N'-diMethyl-N-2-pyridylethylen
2-(benzyl[2-dimethylaminoethyl]amino)pyridine
2-[BENZYL(2-DIMETHYLAMINOETHYL)AMINO]PYRIDINE HYDROCHLORIDE
2-(benzyl(2-(dimethylamino)ethyl)amino)-pyridinhydrochloride
n-benzyl-n-dimethylaminoethylalpha-aminopyridinehydrochloride
n-benzyl-n’,n’-dimethyl-n-2-pyridyl-ethylenediaminehydrochloride
2-(benzyl(2-(dimethylamino)ethyl)amino)-pyridinmonohydrochloride
N-benzyl-N-(2-(dimethylamino)ethyl)pyridin-2-amine hydrochloride
2-(benzyl(2-(dimethylamino)ethyl)amino)pyridinemonohydrochloride
n,n-dimethyl-n’-(2-pyridyl)-n’-benzylethylenediaminehydrochloride
n-benzyl-n’,n’-dimethyl-n-(2-pyridyl)-ethylenediaminhydrochloride
n-benzyl-n-alpha-pyridyl-n’,n’-dimethyl-aethylendiamin-hydrochlorid
PYRIDINE,2-(BENZYL(2-(DIMETHYLAMINO)ETHYL)AMINO)-,MONOHYDROCHLORIDE
Chloropyramine Impurity 1 HCl (Tripelennamine HCl, Pyribenzamine HCl)
Ethylenediamine, N-benzyl-N',N'-dimethyl-N-(2-pyridyl)-, hydrochloride
N-Benzyl-N',N'-dimethyl-N-pyridin-2-yl-ethane-1,2-diamine HYDROCHLORIDE
2-ethanediamine,n,n-dimethyl-n’-(phenylmethyl)-n’-2-pyridinyl-monohydroc
n(sup1)-alpha-pyridyl-n(sup1)-benzyl-n,n-dimethylethylenediaminemonohydro
N1-Benzyl-N2,N2-dimethyl-N1-(pyridin-2-yl)ethane-1,2-diamine hydrochloride
N,N-dimethyl-N'-(phenylmethyl)-N'-(2-pyridinyl)ethane-1,2-diamine hydrochloride
N1,N1-Dimethyl-N2-(phenylmethyl)-N2-(2-pyridinyl)-1,2-ethanediamine hydrochloride
1,2-Ethanediamine, N,N-dimethyl-N'-(phenylmethyl)-N'-2-pyridinyl-, monohydrochloride
N(Sup 1)-.alpha.-pyridyl-N(sup 1)-benzyl-N,N-dimethyl ethylenediamine monohydrochloride
1,2-Ethanediamine,N1,N1-dimethyl-N2-(phenylmethyl)-N2-2-pyridinyl-, hydrochloride (1:1)
2-(Benzyl[2-dimethylaminoethyl]amino)pyridine, N-Benzyl-Nμ,Nμ-dimethyl-N-(2-pyridyl)ethylenediamine hydrochloride | [EINECS(EC#)]
205-833-5 | [Molecular Formula]
C16H22ClN3 | [MDL Number]
MFCD00012815 | [MOL File]
154-69-8.mol | [Molecular Weight]
291.82 |
| Chemical Properties | Back Directory | [Melting point ]
192-193℃ | [density ]
1.20 | [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [solubility ]
DMSO : 25 mg/mL (85.67 mM; Need ultrasonic) | [form ]
neat | [color ]
White to off-white | [Major Application]
cleaning products
cosmetics
food and beverages
forensics and toxicology
personal care
pharmaceutical (small molecule)
veterinary | [InChI]
InChI=1S/C16H21N3.ClH/c1-18(2)12-13-19(16-10-6-7-11-17-16)14-15-8-4-3-5-9-15;/h3-11H,12-14H2,1-2H3;1H | [InChIKey]
FSSICIQKZGUEAE-UHFFFAOYSA-N | [SMILES]
N(CCN(C)C)(CC1=CC=CC=C1)C1=NC=CC=C1.Cl | [EPA Substance Registry System]
Tripelennamine hydrochloride (154-69-8) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
22-36/37/38 | [Safety Statements ]
26-36 | [WGK Germany ]
3
| [RTECS ]
US3150000
| [HS Code ]
2933399090 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 | [Toxicity]
LD50 in mice (mg/kg): 47 i.p. (Walker) |
| Hazard Information | Back Directory | [Chemical Properties]
White Solid | [Uses]
antihistaminic;histamine H1 antagonist | [Uses]
Tripelennamine is a first-generation antihistamine, used in the treatment of asthma, hay fever, and urticaria. | [Brand name]
PBZ (Novartis). | [General Description]
Odorless white crystalline powder or solid. Bitter taste. Solutions are neutral to litmus. pH of aqueous solution (25 mg/mL): 6.71. pH of aqueous solution (50 mg/mL): 6.67. pH of aqueous solution (100 mg/mL): 5.56. | [General Description]
Tripelennamine hydrochlorideis a white crystalline powder that darkensslowly on exposure to light. The salt is soluble in water(1:0.77) and in alcohol (1:6). It has a pKa of about 9, and a0.1% solution has a pH of about 5.5.
Tripelennamine, the first ethylenediamine developed inthe United States and is well absorbed when given orally. Itappears to be as effective as diphenhydramine and may havethe advantage of fewer and less severe side reactions.Drowsiness may occur, however, and may impair the abilityto perform tasks requiring alertness. The concurrent use ofalcoholic beverages should be avoided. | [Air & Water Reactions]
Water soluble. | [Reactivity Profile]
TRIPELENNAMINE HYDROCHLORIDE behaves as a weak organic acid. Materials in this group are generally soluble in water. The resulting solutions contain moderate concentrations of hydrogen ions and have pH's of less than 7.0. They react as acids to neutralize bases. These neutralizations generate heat, but less or far less than is generated by neutralization of inorganic acids, inorganic oxoacids, and carboxylic acid. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible. | [Fire Hazard]
Flash point data for TRIPELENNAMINE HYDROCHLORIDE are not available; however, TRIPELENNAMINE HYDROCHLORIDE is probably combustible. | [Veterinary Drugs and Treatments]
Antihistamines are used in veterinary medicine to reduce or help
prevent histamine mediated adverse effects. Tripelennamine has
been used as a CNS stimulant in “Downer cows” when administered
slow IV. |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Spectrum Chemical Manufacturing Corp.
|
| Telephone: |
021-021-021-67601398-809-809-809 15221380277 |
| Website: |
www.spectrumchemical.com/oa_html/index.jsp?minisite=10020&respid=22372&language=us |
| Company Name: |
LETOPHARM LIMITED
|
| Telephone: |
+86-21-5821 5861 |
| Website: |
www.letopharm.com |
|