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154771-33-2

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154771-33-2 Structure

154771-33-2 Structure
IdentificationBack Directory
[Name]

N-[1-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-2-fluoro-beta-D-arabinofuranosyl]-1,2-dihydro-2-oxo-4-pyrimidinyl]benzamide
[CAS]

154771-33-2
[Synonyms]

DMT-2'-F-Bz-dC
5'-DMT-2'-F-Bz-dC
DMT-2'-F-Bz-dC
5-O-DMT-N4-Bz-2-ara-F-2-dC
5-O-DMT-N4-benzoyl-2'-Fluoro-β-D-arabinofuranosyl-
1-[2-FLUORO-2-DEOXY-5-O-DMTr-Β-D- ARABINOFURANOSYL]-N4-BENZOYL-CYTOSINE
N4-Benzoyl-5’-O-(4,4’-dimethoxytrityl)-2’-deoxy-2’-fluoro-β-Darabinocytidine
N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxy-2'-fluoro--D-arabinocytidine
N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxy-2'-fluoro-b-D-arabinocytidine
5-O-(4,4'-dimethoxytrityl)-N4-benzoyl-2'-fluoro-β-D-arabinofuranosyl-2'-deoxycytidine
5-O-(4,4'-Dimethoxytrityl)-N4-benzoyl-2'-fluoro-b-D-arabinofuranosyl-2'-deoxycytidine
5-O-(4,4'-dimethoxytrityl)-N4-benzoyl-2'-fluoro-β-D-arabinofuranosyl-2'-deoxycytidine
N-(1-((2R,3S,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-fluoro-4-hydroxytetrahyd
N-(1-((2R,3S,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-fluoro-4-hydroxytetrahydrof
N-[1-(5-{[BIS(4-METHOXYPHENYL)(PHENYL)METHOXY]METHYL}-3-FLUORO-4-HYDROXYOXOLAN-2-YL)-2-OXOPYRIMIDIN-
N-{1-{5-O-[Bis-(4-methoxyphenyl)-phenylmethyl]-2-deoxy-2-fluoro--D-arabinofuranosyl}-1,2-dihydro-2-oxo-4-pyrimidinyl}-benzamide
N-[1-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-2-fluoro-beta-D-arabinofuranosyl]-1,2-dihydro-2-oxo-4-pyrimidinyl]benzamide
Benzamide, N-[1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-2-fluoro-β-D-arabinofuranosyl]-1,2-dihydro-2-oxo-4-pyrimidinyl]-
[EINECS(EC#)]

2017-001-1
[Molecular Formula]

C37H34FN3O7
[MDL Number]

MFCD23135324
[MOL File]

154771-33-2.mol
[Molecular Weight]

651.68
Chemical PropertiesBack Directory
[density ]

1.30
[storage temp. ]

2-8°C
[pka]

8.52±0.20(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319
[Precautionary statements ]

P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
Hazard InformationBack Directory
[Uses]

DMT-2'-F-Bz-dC is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].
[References]

[1] Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8. DOI:10.4161/cbt.3.11.1308
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