| Identification | Back Directory | [Name]
4-FLUORO-N-[2-[4-(2-METHOXYPHENYL)PIPERAZIN-1-YL]ETHYL]-N-PYRIDIN-2-YLBENZAMIDE | [CAS]
155204-26-5 | [Synonyms]
MPPF
p-MPPF
P-MPPF DIHYDROCHLORIDE \ 5-HT1A SEROTONI
4-FLUORO-N-[2-[4-(2-METHOXYPHENYL)PIPERAZIN-1-YL]ETHYL]-N-PYRIDIN-2-YLBENZAMIDE
BENZAMIDE, 4-FLUORO-N-[2-[4-(2-METHOXYPHENYL)-1-PIPERAZINYL]ETHYL]-N-2-PYRIDINYL- | [Molecular Formula]
C25H27FN4O2 | [MDL Number]
MFCD08061447 | [MOL File]
155204-26-5.mol | [Molecular Weight]
434.51 |
| Chemical Properties | Back Directory | [Appearance]
Colourless solid | [Boiling point ]
614.4±55.0 °C(Predicted) | [density ]
1.228±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C
| [solubility ]
ethanol: 15 mg/mL
| [form ]
solid
| [pka]
6.68±0.40(Predicted) | [color ]
white
| [CAS DataBase Reference]
155204-26-5 |
| Hazard Information | Back Directory | [Chemical Properties]
Colourless solid | [Uses]
p-MPPF is a selective 5-HT antagonist that dose-dependently antagonizes the reduction of phosphorylated Erk1/2 levels in the hippocampus induced by 8-OH-DPAT (HY-112061) in rats. p-MPPF can be used for neurological disease research[1]. | [References]
[1] Chen J, et al. 5-HT1A receptor-mediated regulation of mitogen-activated protein kinase phosphorylation in rat brain. Eur J Pharmacol. 2002 Oct 4;452(2):155-62. DOI:10.1016/s0014-2999(02)02297-5 |
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