| Identification | Back Directory | [Name]
CEREULIDE, 10ΜG/ML IN ETHANOL | [CAS]
157232-64-9 | [Synonyms]
CEREULIDE, 10ΜG/ML IN ETHANOL
cyclo[-Val-D-O-Leu-D-Ala-O-Val-]3
Cyclo[D-alanyl-(2S)-2-hydroxy-3-methylbutanoyl-L-valyl-(2R)-2-hydroxy-4-methylpentanoyl-D-alanyl-(2S)-2-hydroxy-3-methylbutanoyl-L-valyl-(2R)-2-hydroxy-4-methylpentanoyl-D-alanyl-(2S)-2-hydroxy-3-methylbutanoyl-L-valyl-(2R)-2-hydroxy-4-methylpentanoyl] | [Molecular Formula]
C57H96N6O18 | [MOL File]
157232-64-9.mol | [Molecular Weight]
1153.42 |
| Chemical Properties | Back Directory | [Boiling point ]
1341.5±65.0 °C(Predicted) | [density ]
1.044±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
Soluble in DMSO or Ethanol | [form ]
liquid | [pka]
11.33±0.70(Predicted) | [color ]
Colourless | [Stability:]
Stable for 1 year from date of purchase as supplied. Diluted solutions in DMSO or ethanol may be stored at -20°C for up to 3 months. |
| Hazard Information | Back Directory | [Description]
Cereulide (CAS 157232-64-9) is an emetic toxin produced by?Bacillus cereus. Acts as an ionophore with high selectivity for K+. Stimulates swelling and respiration in rat liver mitochondria.1? It is a lipophilic cyclopeptide and is rapidly absorbed in the gut and transported into the bloodstream. The causative agent in various forms of gastroenteritic disease associated with food poisoning.2
WARNING: Exercise caution when handling and using this compound.? Avoid exposure. | [Uses]
Cereulide, a toxin depsipeptide, can be produced by Bacillus cereus. Cereulide induces cell apoptosis. Cereulide acts on mitochondria, leading to dysfunction in different organs (liver, pancreatic islet, brain, intestines, etc.) and body systems (immune system and nervous system)[1]. | [References]
1) Mikkola?et al. (1999),?Ionophoretic properties and mitochondrial effects of cereulide: the emetic toxin of B. cereus; Eur. J. Biochem.,?263?112
2) Ehling-Schulz?et al.?(2004),?Bacillus cereus, the causative agent of an emetic type of food-borne illness; Mol. Nutri.,?48?479 |
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| Company Name: |
Merck KGaA
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| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
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