| Identification | Back Directory | [Name]
1-METHYLADENOSINE | [CAS]
15763-06-1 | [Synonyms]
1-METHYLADENOSINE
Adenosine, 1-methyl-
1-methyladenosine free base
N,6-Didehydro-1,6-dihydro-1-methyladenosine
(2R,3R,4R,5R)-2-(hydroxymethyl)-5-(6-imino-1-methyl-purin-9-yl)oxolane-3,4-diol
(2R,3R,4S,5R)-2-(6-Amino-1-methyl-1H-purin-9(2H)-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol | [Molecular Formula]
C11H15N5O4 | [MDL Number]
MFCD00038421 | [MOL File]
15763-06-1.mol | [Molecular Weight]
281.27 |
| Chemical Properties | Back Directory | [Melting point ]
>217°C (dec.) | [Boiling point ]
655.4±65.0 °C(Predicted) | [density ]
1.88±0.1 g/cm3(Predicted) | [storage temp. ]
−20°C | [solubility ]
DMSO (Slightly), Water (Slightly, Sonicated) | [form ]
Solid | [pka]
13.24±0.70(Predicted) | [color ]
White to Off-White | [Stability:]
Hygroscopic, Light Sensitive |
| Hazard Information | Back Directory | [Description]
1-Methyladenosine is a modified nucleoside generated by the processing of tRNA by methyltransferases.1,2,3 The urinary excretion of 1-methyladenosine is elevated in several forms of cancer, supporting its use as a biomarker in early detection.4,5,6 It can also be monitored in serum.7 Urinary levels of 1-methyladenosine also increase during active rheumatoid arthritis.8 | [Chemical Properties]
White to off-white crystalline powder | [Uses]
1-Methyl Adenosine is a modified adenosine molecule created through the processing of tRNA by methyltransferases. The presence seen to be elevated in the urinary excretion of cancer patients. Thus it may be an early diagnosis biomarker. | [Definition]
ChEBI: A methyladenosine carrying a methyl substituent at position 1. |
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