| Identification | Back Directory | [Name]
2-AMINO-4-(3,4-DIMETHOXY-PHENYL)-THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER | [CAS]
15854-12-3 | [Synonyms]
aPKC-IN-1
Ethyl 2-amino-4-(3,4-dimethoxyphenyl)-3-thiophenecarboxylate
2-amino-4-(3,4-dimethoxyphenyl)-3-thiophenecarboxylic acid ethyl ester
3-Thiophenecarboxylic acid, 2-amino-4-(3,4-dimethoxyphenyl)-, ethyl ester | [Molecular Formula]
C15H17NO4S | [MDL Number]
MFCD00499458 | [MOL File]
15854-12-3.mol | [Molecular Weight]
307.36 |
| Chemical Properties | Back Directory | [Boiling point ]
437.3±45.0 °C(Predicted) | [density ]
1.234±0.06 g/cm3(Predicted) | [form ]
solid | [pka]
-0.29±0.10(Predicted) | [InChI]
1S/C15H17NO4S/c1-4-20-15(17)13-10(8-21-14(13)16)9-5-6-11(18-2)12(7-9)19-3/h5-8H,4,16H2,1-3H3 | [InChIKey]
OZWGHIQPWZHYPG-UHFFFAOYSA-N | [SMILES]
[s]1c(c(c(c1)c2cc(c(cc2)OC)OC)C(=O)OCC)N |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
22-41 | [Safety Statements ]
26-39 | [WGK Germany ]
3 | [HS Code ]
2934999090 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral
Eye Dam. 1 |
| Hazard Information | Back Directory | [Uses]
aPKC-IN-1 (compound 1) is an atypical protein kinase C (aPKCζ) inhibitor. aPKC-IN-1 can be used for the study of a host of diseases involving increased vascular permeability and inflammation[1]. | [References]
[1] Paul M Titchenellm, et al. Synthesis and structure-activity relationships of 2-amino-3-carboxy-4-phenylthiophenes as novel atypical protein kinase C inhibitors. Bioorg Med Chem Lett. 2013 May 15;23(10):3034-8. DOI:10.1016/j.bmcl.2013.03.019 |
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| Company Name: |
Energy Chemical
|
| Telephone: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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