ChemicalBook--->CAS DataBase List--->158841-76-0

158841-76-0

158841-76-0 Structure

158841-76-0 Structure
IdentificationBack Directory
[Name]

AC-ARG-CYS-GLY-VAL-PRO-ASP-NH2
[CAS]

158841-76-0
[Synonyms]

AC-RCGVPD-NH2
MMP-3 INHIBITOR I
Reaxys ID: 15522609
MMP PEPTIDE INHIBITOR I
STROMELYSIN-1 INHIBITOR
AC-ARG-CYS-GLY-VAL-PRO-ASP-NH2
Matrix Metalloproteinase-3 Inhibitor
MMP-3 INHIBITOR;MATRIX METALLOPROTEINASE-3 INHIBITOR
L-α-Asparagine, N2-acetyl-L-arginyl-L-cysteinylglycyl-L-valyl-L-prolyl-
Acetyl-StroMelysin-1 Activation Peptide (74-79) aMide (huMan, horse, Mouse), Acetyl-MMP-3 Precursor (91-96) aMide (huMan, horse, Mouse)
[Molecular Formula]

C27H46N10O9S
[MDL Number]

MFCD01310938
[MOL File]

158841-76-0.mol
[Molecular Weight]

686.78
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[solubility ]

DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 10 mg/ml
[form ]

White to off-white solid.
[color ]

white
[Water Solubility ]

water: 1mg/mL
[Sequence]

Ac-Arg-Cys-Gly-Val-Pro-Asp-NH2
Safety DataBack Directory
[WGK Germany ]

WGK 1
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Uses]

MMP3 inhibitor 3 is an inhibitor of MMP3. MMP3 inhibitor 3 can used to study breast cancer[1].
[Biological Activity]

Cell permeable: no''Primary Target
MMP-3''Product does not compete with ATP.''Reversible: no''Target IC50: 5 μM against MMP-3
[References]

[1] Holliday DL, et al. Intrinsic genetic characteristics determine tumor-modifying capacity of fibroblasts: matrix metalloproteinase-3 5A/5A genotype enhances breast cancer cell invasion. Breast Cancer Res. 2007;9(5):R67. DOI:10.1186/bcr1775
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