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1594121-16-0

1594121-16-0 Structure

1594121-16-0 Structure
IdentificationBack Directory
[Name]

SR-8993
[CAS]

1594121-16-0
[Synonyms]

SR-8993
[Molecular Formula]

C25H37FN4
[MOL File]

1594121-16-0.mol
[Molecular Weight]

412.59
Chemical PropertiesBack Directory
[Boiling point ]

578.6±50.0 °C(Predicted)
[density ]

1.26±0.1 g/cm3(Predicted)
[pka]

9.68±0.10(Predicted)
Hazard InformationBack Directory
[Description]

SR8993 is a highly selective, brain-penetrant nociceptin receptor (NOP) agonist.
[Uses]

SR-8993 is a highly selective nociceptin receptor agonist that can penetrate the blood-brain barrier and has the activity of reducing alcohol intake and relieving withdrawal anxiety. SR-8993 has shown mild anxiolytic effects in animal models and can effectively reverse anxiety caused by acute alcohol withdrawal. SR-8993 further reduces restricted drinking, operant responses for alcohol, and increased drinking induced by long-term intermittent exposure to alcohol. SR-8993 also reduces stress- and cue-related alcohol-seeking relapse[1].
[References]

[1] The nociceptin/orphanin FQ receptor agonist SR-8993 as a candidate therapeutic for alcohol use disorders: validation in rat models
1594121-16-0 suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354; +17819995354 , +17819995354
Website: https://www.targetmol.com/
Company Name: TargetMol Chemicals Inc.
Tel: +17819995354 , +17819995354
Website:
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
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