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159857-60-0

159857-60-0 Structure

159857-60-0 Structure
IdentificationBack Directory
[Name]

N-alpha-Fmoc-N-epsilon-4-methoxytrityl-L-lysine
[CAS]

159857-60-0
[Synonyms]

(S)-2-((((9H-Fluo
N2-FMOC protected
FMOC-LYS(MMT)-OH 1 G
FMOC-LYS(MMT)-OH 5 G
N6-(4-Methoxytrityl)-L-lysine
Nα-Fmoc-Nε-4-methoxyyltrityl-L-lysine
N-alpha-Fmoc-Nε-4-methoxyyltrityl-L-lysine
(9H-Fluoren-9-yl)MethOxy]Carbonyl Lys(MMt)-OH
N6-(4-Methoxytrityl)-L-lysine, N2-FMOC protected
N-Fmoc-N'-[(4-methoxyphenyl)methyldiphenyl]-L-lysine
Nα-Fmoc-Nε-4-methoxyyltrityl-L-lysine≥ 99.8% (HPLC, Chiral purity)
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N'-[(4-methoxyphenyl)diphenylmethyl]-L-lysine
N2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N6-((4-methoxyphenyl)diphenylmethyl)-L-lysine
L-Lysine, N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-N6-[(4-methoxyphenyl)diphenylmethyl]-
N6-[Diphenyl(4-methoxyphenyl)methyl]-N2-{[(9H-fluoren-9-yl)methoxy]carbonyl}-L-lysine
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-(((4-Methoxyphenyl)diphenylmethyl)amino)he
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-(((4-Methoxyphenyl)diphenylmethyl)amino)hexan
N6-[Diphenyl(4-methoxyphenyl)methyl]-N2-{[(9H-fluoren-9-yl)methoxy]carbonyl}-L-lysine, FMOC-L-LYS(MMT)-OH
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-(((4-Methoxyphenyl)diphenylmethyl)amino)hexanoic acid
(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-6-{[(4-methoxyphenyl)diphenylmethyl]amino}hexanoic acid
(S)-2-(((9H-fluoren-9-yl)methyl9H-fluoren-9-yl)methoxy)carbonylamino)-6-((4-methoxyphenyl)diphenylmethylamino)hexanoic acid
[Molecular Formula]

C41H40N2O5
[MDL Number]

MFCD00270542
[MOL File]

159857-60-0.mol
[Molecular Weight]

640.77
Chemical PropertiesBack Directory
[Boiling point ]

814.1±65.0 °C(Predicted)
[density ]

1.210
[storage temp. ]

Store at +2°C to +8°C.
[form ]

solid
[pka]

3.83±0.21(Predicted)
[color ]

off-white
[Major Application]

peptide synthesis
[InChIKey]

CTYHQVFFQRDJSN-LHEWISCISA-N
[SMILES]

C(O)(=O)[C@H](CCCCNC(C1=CC=C(OC)C=C1)(C1=CC=CC=C1)C1=CC=CC=C1)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P280-P261
[WGK Germany ]

WGK 3
[HS Code ]

2924297099
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Chemical Properties]

White to pale brown solid
[Uses]

peptide synthesis
[General Description]

An excellent derivative for the synthesis of branched peptides and peptides modified at the lysine side-chain [1], and for the construction of templates and multifunctionalized resins for combinatorial synthesis.

The side-chain Mmt group can be selectively removed in the same manner as Mtt with 1% TFA in DCM [2, 3, 4] or DCM/HFIP/TFE/TES (6.5:2:1:0.5) [5]. Alternatively, it can be removed under milder conditions with AcOH/TFE/DCM (1:2:7) [1], leaving Mtt intact.

The product number for this product was previously 04-12-1232.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.
[reaction suitability]

reaction type: Fmoc solid-phase peptide synthesis
Spectrum DetailBack Directory
[Spectrum Detail]

N-alpha-Fmoc-N-epsilon-4-methoxytrityl-L-lysine(159857-60-0)1HNMR
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