ChemicalBook--->CAS DataBase List--->159857-79-1

159857-79-1

159857-79-1 Structure

159857-79-1 Structure
IdentificationBack Directory
[Name]

Val-cit-PAB-OH
[CAS]

159857-79-1
[Synonyms]

EOS-61316
al-Cit-PAB-OH
Val-cit-PAB-OH
NH2-Val-Cit-PAB
(D)-VAL-CIT-PAB
L-Valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-L-ornithinamide
L-Ornithinamide, L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-
(S)-2-((R)-2-amino-3-methylbutanamido)-N-(4-(hydroxymethyl)phenyl)-5-ureidopentanamide
(S)-2-((S)-2-amino-3-methylbutanamido)-N-(4-(hydroxymethyl)phenyl)-5-ureidopentanamide
[EINECS(EC#)]

826-617-2
[Molecular Formula]

C18H29N5O4
[MDL Number]

MFCD22381209
[MOL File]

159857-79-1.mol
[Molecular Weight]

379.45
Chemical PropertiesBack Directory
[Melting point ]

168 °C(dec.)
[Boiling point ]

715.0±60.0 °C(Predicted)
[density ]

1.243±0.06 g/cm3(Predicted)
[storage temp. ]

Keep in dark place,Sealed in dry,2-8°C
[solubility ]

DMF: 10 mg/ml; DMSO: 10 mg/ml; PBS (pH 7.2): 1 mg/ml
[form ]

powder to crystal
[pka]

13.75±0.46(Predicted)
[color ]

White to Almost white
Safety DataBack Directory
[HS Code ]

2924.29.7790
Hazard InformationBack Directory
[Description]

Val-Cit-PAB-OH is a peptide cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). The Val-Cit will specifically be cleaved by Cathepsin B.
[Uses]

Val-cit-PAB-OH acts as a reagent in the preparation of cell-penetrating peptidic GRP78 ligand for tumor cell-specific prodrug therapy, preparation of monomethylvaline derivative conjugates with ligands and antibodies for cancer treatment.
159857-79-1 suppliers list
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: +86-0371-55170693 +86-19937530512 , +86-19937530512
Website: https://www.tianfuchem.com/
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Website: www.atkchemical.com
Company Name: Shenzhen Nexconn Pharmatechs Ltd
Tel: +86-755-89396905 +86-15013857715 , +86-15013857715
Website: https://www.chemicalbook.com/ShowSupplierProductsList31188/0.htm
Company Name: Jinan Carbotang Biotech Co.,Ltd.
Tel: +8615866703830 , +8615866703830
Website: https://www.chemicalbook.com/ShowSupplierProductsList31189/0.htm
Company Name: BOC Sciences
Tel: +1-631-485-4226
Website: www.bocsci.com/
Company Name: career henan chemical co
Tel: +86-0371-86658258 15093356674; , 15093356674;
Website: http://www.coreychem.com
Company Name: Zhengzhou Alfa Chemical Co.,Ltd
Tel: +8618530059196 , +8618530059196
Website: https://www.chemicalbook.com/manufacturer/zhengzhou-alfa-chemical-276/
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000 , +1-00000000000
Website: https://www.targetmol.com/
Company Name: NINGBOBENKANGJS PHARMTECHCO., LTD
Tel: +8615990591583 15990591583 , 15990591583
Website: nbpharmabridge.com/en
Company Name: HANGZHOU CLAP TECHNOLOGY CO.,LTD
Tel: 86-571-88216897,88216896 13588875226 , 13588875226
Website: www.hzclap.com/en
Company Name: Shanxi Xuanran Import and Export Trade Co., Ltd.
Tel: +8617735180244 , +8617735180244
Website: www.xuanranglobal.com
Company Name: KARMEL TECHNOLOGY (HK) CO.,LIMITED
Tel: +8618795957998 , +8618795957998
Website: www.chemicalbook.com/ShowSupplierProductsList1620060/0.htm
Company Name: ANHUI WITOP BIOTECH CO., LTD
Tel: +8615255079626 , +8615255079626
Website: www.chemicalbook.com/showsupplierproductslist418627/0_en.htm
Company Name: Zhejiang J&C Biological Technology Co.,Limited
Tel: +1-2135480471 +1-2135480471 , +1-2135480471
Website: https://www.sarms4muscle.com
Company Name: Hangzhou Huarong Pharm Co., Ltd.
Tel: 571-86758373 +8613588754946 , +8613588754946
Website: https://www.huarongpharm.com/
Company Name: ChemExpress
Tel: +86-021-58950125
Website: www.chemexpress.com
Company Name: Nextpeptide Inc
Tel: +86-0571-81612335 +8613336028439 , +8613336028439
Website: http://www.nextpeptide.com/
Company Name: Labnetwork lnc.
Tel: +86-27-50766799 +8618062016861 , +8618062016861
Website: www.labnetwork.com
Tags:159857-79-1 Related Product Information
106362-32-7 932699-03-1 863971-53-3 1099731-44-8 159858-21-6 159858-22-7 159857-80-4