| Identification | Back Directory | [Name]
M090 | [CAS]
1599466-63-3 | [Synonyms]
M090
2-Thiophenemethanamine, 3-cyclopropyl-N-[(1R,2R,3R,5S)-2,6,6-trimethylbicyclo[3.1.1]hept-3-yl]- | [Molecular Formula]
C18H27NS | [MOL File]
1599466-63-3.mol | [Molecular Weight]
289.48 |
| Chemical Properties | Back Directory | [Boiling point ]
383.0±27.0 °C(Predicted) | [density ]
1.09±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [form ]
oil | [pka]
9.59±0.60(Predicted) | [color ]
colorless to very dark brown | [InChI]
1S/C18H27NS/c1-11-15-8-13(18(15,2)3)9-16(11)19-10-17-14(6-7-20-17)12-4-5-12/h6-7,11-13,15-16,19H,4-5,8-10H2,1-3H3/t11-,13+,15-,16-/m1/s1 | [InChIKey]
MTOZOUMZDHSFBE-WXYCVUISSA-N | [SMILES]
C[C@H]1[C@H](NCC2=C(C3CC3)C=CS2)C[C@H]4C(C)(C)[C@@H]1C4 |
| Hazard Information | Back Directory | [Uses]
M090 is the inhibitor for the hemagglutinin of influenza A Virus, that inhibits various influenza strains with EC50 of micromolar levels[1]. | [Biological Activity]
M090 is a potent inhibitor of influenza A hemagglutinin th at is effective against amantadine-resistant and oseltamivir-resistant viruses. | [References]
[1] Valdivia A, et al., Mining Druggable Sites in Influenza A Hemagglutinin: Binding of the Pinanamine-Based Inhibitor M090[J]. ACS Medicinal Chemistry Letters, 2024. |
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| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
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