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160036-44-2

160036-44-2 Structure

160036-44-2 Structure
IdentificationBack Directory
[Name]

(2S)-2-{2-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)acetamido]acetamido}-3-phenylpropanoic acid
[CAS]

160036-44-2
[Synonyms]

(2S)-2-{2-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)acetamido]acetamido}-3-phenylpropanoic acid
[Molecular Formula]

C28H27N3O6
[MDL Number]

MFCD33023222
[MOL File]

160036-44-2.mol
[Molecular Weight]

501.53
Chemical PropertiesBack Directory
[Boiling point ]

852.2±65.0 °C(Predicted)
[density ]

1.315±0.06 g/cm3(Predicted)
[form ]

Solid
[pka]

3.50±0.10(Predicted)
[color ]

White to off-white
[InChIKey]

UFGUUZVZUIXKQZ-DEOSSOPVSA-N
[SMILES]

C(O)(=O)[C@H](CC1=CC=CC=C1)NC(=O)CNC(=O)CNC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319
[Precautionary statements ]

P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330
Hazard InformationBack Directory
[Description]

Fmoc-Gly-Gly-Phe-OH is an Fmoc-protected glycine derivative with a carboxylate group at the α position and an amide group at the β position. It is a white solid that can be synthesized by the reaction of ethyl glycine with glyoxylic acid in a solvent such as chloroform. This compound can be used for proteomic research and solid-phase peptide synthesis technology. It has been used to study the binding of oxytocin to its receptor, which is important in regulating uterine contractions during labor.
[Uses]

Fmoc-Gly-Gly-Phe-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
[IC 50]

Cleavable Linker
[storage]

-20℃ 3 years powder; -80℃ 2 years in solvent
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