| Identification | Back Directory | [Name]
L-KYNURENINE SULFATE | [CAS]
16055-80-4 | [Synonyms]
L-KYNURENINESULPHATE
L-Kynurenine sulfate salt crystalline
L-KYNURENINE SULFATE (SALT) MONOHYDRATE
L-Kynurenine sulphate (salt) monohydrate
L-2-AMINO-3-(2-AMINOBENZOYL)PROPIONIC ACID SULFATE SALT
Benzenebutanoic acid, a,2-diaMino-g-oxo-, (aS)-, sulfate (1:1)
Benzenebutanoic acid, α,2-diamino-γ-oxo-, (αS)-, sulfate (1:1)
L-KYNURENINE SULFATE (RING-D4, 3,3-D2, 97%+) 95% CHEMICAL PURITY
(S)-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid sulfuric acid salt
(S)-2-Amino-4-(2-Aminophenyl)-4-Oxobutanoic Acid Compound With Sulfuric Acid
(S)-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid compound with sulfuric acid (1:1) | [Molecular Formula]
C10H16N2O8S | [MDL Number]
MFCD04966494 | [MOL File]
16055-80-4.mol | [Molecular Weight]
324.308 |
| Chemical Properties | Back Directory | [Melting point ]
196 °C (decomp) | [storage temp. ]
−20°C | [form ]
crystalline | [color ]
light yellow | [InChI]
1S/C10H12N2O3.H2O4S/c11-7-4-2-1-3-6(7)9(13)5-8(12)10(14)15;1-5(2,3)4/h1-4,8H,5,11-12H2,(H,14,15);(H2,1,2,3,4)/t8-;/m0./s1 | [InChIKey]
KAXRWMOLNJZCEW-QRPNPIFTSA-N | [SMILES]
OS(O)(=O)=O.N[C@@H](CC(=O)c1ccccc1N)C(O)=O |
| Hazard Information | Back Directory | [Uses]
L-Kynurenine Sulfate is a tryptophan metabolite which is a precursor of kynurenic acid (K660500) and an antagonist of N-methyl-aspartate receptor. | [Biological Activity]
L-Kynurenine (L-Kyn) is a precursor of kynurenic acid which is the only recognized endogenous excitatory amino acid receptor antagonist in the central nervous system. L-Kyn is known to be a pigment generating component in animals. In mammalsit modulates the transmission of glutamate neurotransmitter. It is also considered to be a sex-attracting pheromone in vertebrates.''L-Kynurenine is a key intermediate in the breakdown of L-tryptophan and the formation of nicotinamide adenine dinucleotide (NAD+) via the kynurenine pathway. L-kynurenine is involved in a variety of neurological processes and diseases. L-kynurenine is a substrate for kynureninase/kynurenine hydrolase; kynurenine 3-monooxygenase and kynurenine-oxoglutarate transaminase.''Key intermediate in the breakdown pathway of tryptophan. | [IC 50]
Human Endogenous Metabolite | [Purification Methods]
Crystallise the sulfate from water by addition of EtOH. The (±)-sulfate has m 173o. [Beilstein 14 IV 2562.] |
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