| Identification | Back Directory | [Name]
22bH-18,22a-(Iminomethano)-10b,23a-methano-10bH,23aH-indolo[2′′,3′′:2′,3′][1,2,3,4,6]tetrathiazocino[6′′,5′′:1′,5′]pyrrolo[3′,4′:6,7]pyrazino[2′′′,1′′′:2,3][1,3]oxazepino[4,5-b]indole-1,4,17,25(18H)-tetrone, 2,3,5a,6,15,15a-hexahydro-24-hydroxy-3-(hydroxymethyl)-2,26-dimethyl-18-(1-methylethyl)-, (3R,5aR,10bS,10cR,15aS,18R,22aR,22bR,23aR,24R)-rel-(+)- | [CAS]
160550-15-2 | [Synonyms]
Leptosin J
22bH-18,22a-(Iminomethano)-10b,23a-methano-10bH,23aH-indolo[2′′,3′′:2′,3′][1,2,3,4,6]tetrathiazocino[6′′,5′′:1′,5′]pyrrolo[3′,4′:6,7]pyrazino[2′′′,1′′′:2,3][1,3]oxazepino[4,5-b]indole-1,4,17,25(18H)-tetrone, 2,3,5a,6,15,15a-hexahydro-24-hydroxy-3-(hydroxymethyl)-2,26-dimethyl-18-(1-methylethyl)-, (3R,5aR,10bS,10cR,15aS,18R,22aR,22bR,23aR,24R)-rel-(+)- | [Molecular Formula]
C32H32N6O7S4 | [MOL File]
160550-15-2.mol | [Molecular Weight]
740.88 |
| Hazard Information | Back Directory | [Uses]
Leptosin J is found in the strain of Leptosphaeria sp. OUPS-4. Leptosin J inhibits Leukemia lymphocyte P388 in culture with an ED50 of 1.25 μg/mL[1]. | [References]
[1] David P Overy, et al. Sea foam as a source of fungal inoculum for the isolation of biologically active natural products. Mycology. 2014 Jul 3;5(3):130-144. |
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