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160568-14-9

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160568-14-9 Structure

160568-14-9 Structure
IdentificationBack Directory
[Name]

zarzissine
[CAS]

160568-14-9
[Synonyms]

zarzissine
1H-Imidazo[4,5-d]pyridazin-2-amine
Zarzissine/1H-Imidazo[45-d]pyridazin-2-amine
[Molecular Formula]

C5H5N5
[MOL File]

160568-14-9.mol
[Molecular Weight]

135.13
Chemical PropertiesBack Directory
[Boiling point ]

565.7±42.0 °C(Predicted)
[density ]

1.612±0.06 g/cm3(Predicted)
[pka]

12.57±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

Zarzissine is a cytotoxic guanidine alkaloid that can be isolated from the Mediterranean sponge Anchinoe paupertas. Zarzissine shows antimicrobial and anticancer activities[1].
[Definition]

ChEBI: A organonitrogen heterocyclic compound that is 1H-imidazo[4,5-d]pyridazine substituted by an amino group at position 2. A guanidine alkaloid isolated from Anchinoe paupertas, it exhibits cytotoxic activity again t human and murine tumor cell lines.
[References]

[1] Bouaicha N, et al. Zarzissine, a new cytotoxic guanidine alkaloid from the Mediterranean sponge Anchinoe paupertas. J Nat Prod. 1994 Oct;57(10):1455-7. DOI:10.1021/np50112a019
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