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1609461-57-5

1609461-57-5 Structure

1609461-57-5 Structure
IdentificationBack Directory
[Name]

1H-Indole-2-carboxamide, N-[3-(2-amino-1H-imidazol-5-yl)phenyl]-5-(trifluoromethoxy)-, hydrochloride (1:1)
[CAS]

1609461-57-5
[Synonyms]

1H-Indole-2-carboxamide, N-[3-(2-amino-1H-imidazol-5-yl)phenyl]-5-(trifluoromethoxy)-, hydrochloride (1:1)
[Molecular Formula]

C19H14F3N5O2.ClH
[MOL File]

1609461-57-5.mol
[Molecular Weight]

437.8
Hazard InformationBack Directory
[Uses]

HV1-IN-1 hydrochloride is an inhibitor of the human voltage-gated proton channel (hHV1). HV1-IN-1 hydrochloride works by binding to the VSD of the HV1 channel. The VSD is a component of the HV1 channel that is responsible for detecting changes in membrane potential and triggering the opening of the channel. HV1-IN-1 hydrochloride can be used in the study of cancer, neuroinflammation and immune response[1].
[References]

[1] Piga M, et al. Identification of a Novel Structural Class of HV1 Inhibitors by Structure-Based Virtual Screening[J]. Journal of Chemical Information and Modeling, 2024. DOI:10.1021/acs.jcim.4c00240
1609461-57-5 suppliers list
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