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161016-55-3

161016-55-3 Structure

161016-55-3 Structure
IdentificationBack Directory
[Name]

PO-PRO 3
[CAS]

161016-55-3
[Synonyms]

PO-PRO 3
Po-pro 3 Iodide
BENZOXAZOLIUM, 3-METHYL-2-[3-[1-[3-(TRIMETHYLAMMONIO)PROPYL]-4(1H)-PYRIDINYLIDENE]-1-PROPENYL]-, DIIODIDE
3-METHYL-2-((E)-3-[1-[3-(TRIMETHYLAMMONIO)PROPYL]-4(1H)-PYRIDINYLIDENE]-1-PROPENYL)-1,3-BENZOXAZOL-3-IUM DIIODIDE
[Molecular Formula]

C22H29I2N3O
[MDL Number]

MFCD06409926
[MOL File]

161016-55-3.mol
[Molecular Weight]

605.29
Chemical PropertiesBack Directory
[Melting point ]

>250℃
[solubility ]

Soluble in dimethyl sulfoxide
[form ]

powder
[color ]

Yellow-brown
[Appearance]

red solution
[ex/em]

539/567 nm
[ε(extinction coefficient)]

87900 cm−1M−1
[λmax]

539 nm
[Φ(quantum yield)]

0.57
[Biological Applications]

Nucleic acid hybridization; detecting nucleic acids,cells; nucleic acid fingerprinting; nucleic acid fragment sizing; nucleic acid amplification
Hazard InformationBack Directory
[Description]

PO-TAP-3 (Oxazole Orange Monomer, also known as PO-PRO®-3) is a yellow fluorescent carbocyanine monomeric dye. PO-TAP-3 is a cell-impermeant nucleic acid stain that is nonfluorescent in the absence of nucleic acids but exhibits a multiple fluorescence enhancement upon binding to dsDNA.


The bright fluorescence signal and low background make PO-TAP-3 ideal for staining nucleic acids on microarrays, as well as for nuclear and chromosome counterstaining in multicolor fluorescence labeling experiments.


The dye is used to image cell nuclei and cytoplasm, label bacteria and sperms, count reticulocytes, perform nucleic acid amplification and hybridization, and as a temperature sensor.

[Chemical Properties]

ex/em: 539/567 nm
Extinction coefficient (ε): 87900 cm??1M??1
Quantum yield (Φ): 0.57
[Definition]

ChEBI: Po-Pro-3 is a cyanine dye and an organic iodide salt. It has a role as a fluorochrome. It contains a Po-Pro-3(2+).
[Abs/Em Maxima]

531 (complex)/568 (complex) nm
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