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1611490-64-2

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1611490-64-2 Structure

1611490-64-2 Structure
IdentificationBack Directory
[Name]

UDP-GlcNAz.2Na
[CAS]

1611490-64-2
[Synonyms]

UDP-GlcNAz.2Na
[Molecular Formula]

C17H27N6NaO17P2
[MOL File]

1611490-64-2.mol
[Molecular Weight]

672.37
Chemical PropertiesBack Directory
[form ]

Solid
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

UDP-GlcNAz disodium is a sugar donor. UDP-GlcNAz disodium serves as a substrate for OGTase and O-GlcNAcase. UDP-GlcNAz disodium can glycosylate p62 and its glycosidic bond can be cleaved by O-GlcNAcase through catalysis. UDP-GlcNAz disodium can be used in the research of related protein glycosylation[1][2].
[References]

[1] Vocadlo DJ, et, al. A chemical approach for identifying O-GlcNAc-modified proteins in cells. Proc Natl Acad Sci U S A. 2003 Aug 5;100(16):9116-21. DOI:10.1073/pnas.1632821100
[2] Kim EJ, et al. Versatile O-GlcNAc transferase assay for high-throughput identification of enzyme variants, substrates, and inhibitors. Bioconjug Chem. 2014 Jun 18;25(6):1025-30. DOI:10.1021/bc5001774
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