| Identification | Back Directory | [Name]
(2R,3S,4S,5R)-2-(2-Amino-9H-purin-9-yl)-4-fluoro-5-(hydroxymethyl)tetrahydrofuran-3-ol | [CAS]
1612192-04-7 | [Synonyms]
9H-Purin-2-amine, 9-(3-deoxy-3-fluoro-β-D-ribofuranosyl)-
2-Amino-9-(3-deoxy-3-fluoro-beta-D-ribofuranosyl)-9H-purine
(2R,3S,4S,5R)-2-(2-Amino-9H-purin-9-yl)-4-fluoro-5-(hydroxymethyl)tetrahydrofuran-3-ol | [Molecular Formula]
C10H12FN5O3 | [MDL Number]
MFCD25542496 | [MOL File]
1612192-04-7.mol | [Molecular Weight]
269.232 |
| Hazard Information | Back Directory | [Uses]
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-9H-purin-2-amine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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