| Identification | Back Directory | [Name]
Desidustat | [CAS]
1616690-16-4 | [Synonyms]
ZYAN1
ZYAN 1
CS-2813
Desidustat
Glycine, N-[[1-(cyclopropylmethoxy)-1,2-dihydro-4-hydroxy-2-oxo-3-quinolinyl]carbonyl]-
Desidustat【(1-(cyclopropylmethoxy)-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carbonyl)glycine】 | [Molecular Formula]
C16H16N2O6 | [MDL Number]
MFCD31630836 | [MOL File]
1616690-16-4.mol | [Molecular Weight]
332.31 |
| Chemical Properties | Back Directory | [Melting point ]
212-214°C | [density ]
1.54±0.1 g/cm3(Predicted) | [storage temp. ]
Hygroscopic, Refrigerator, under inert atmosphere | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
3.61±0.10(Predicted) | [color ]
White to Off-White | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Uses]
Desidustat, is an HIF hydroxylase inhibitor. | [in vivo]
Desidustat (oral; 10-100 mg/kg) has good efficacy in vivo[1]. | Animal Model: |
C57 Mice[1] | | Dosage: | 10, 30, 50, 100 mg/kg;
20 mg /kg
| | Administration: | oral gavage;
oral, once, daily, for 7 days
| | Result: | Significant increased the level of EPO and Hb. |
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