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1616690-16-4

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1616690-16-4 Structure

1616690-16-4 Structure
IdentificationBack Directory
[Name]

Desidustat
[CAS]

1616690-16-4
[Synonyms]

ZYAN1
ZYAN 1
CS-2813
Desidustat
Glycine, N-[[1-(cyclopropylmethoxy)-1,2-dihydro-4-hydroxy-2-oxo-3-quinolinyl]carbonyl]-
Desidustat【(1-(cyclopropylmethoxy)-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carbonyl)glycine】
[Molecular Formula]

C16H16N2O6
[MDL Number]

MFCD31630836
[MOL File]

1616690-16-4.mol
[Molecular Weight]

332.31
Chemical PropertiesBack Directory
[Melting point ]

212-214°C
[density ]

1.54±0.1 g/cm3(Predicted)
[storage temp. ]

Hygroscopic, Refrigerator, under inert atmosphere
[solubility ]

DMSO (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

3.61±0.10(Predicted)
[color ]

White to Off-White
[Stability:]

Hygroscopic
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
Hazard InformationBack Directory
[Uses]

Desidustat, is an HIF hydroxylase inhibitor.
[in vivo]

Desidustat (oral; 10-100 mg/kg) has good efficacy in vivo[1].

Animal Model: C57 Mice[1]
Dosage:10, 30, 50, 100 mg/kg;
20 mg /kg
Administration:oral gavage;
oral, once, daily, for 7 days
Result:Significant increased the level of EPO and Hb.
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