| Identification | Back Directory | [Name]
GLP-1 (9-36) AMIDE (HUMAN, BOVINE, GUINEA PIG, MOUSE, PORCINE, RAT) | [CAS]
161748-29-4 | [Synonyms]
GLP-1 (9-36) amide
PubChem ID: 90488821
GLP-1 (9-36) aMide huMan
GLP-1 (9-36) amide trifluoroacetate
Glucagon Like Peptide-I (9-36) amide, human
GLP-1 (9-36) AMIDE (HUMAN, BOVINE, GUINEA PIG, MOUSE, PORCINE, RAT)
PROGLUCAGON (80-107) AMIDE (HUMAN, BOVINE, GUINEA PIG, MOUSE, PORCINE, RAT)
PREPROGLUCAGON (100-127) AMIDE (HUMAN, BOVINE, GUINEA PIG, MOUSE, PORCINE, RAT)
GLUCAGON-LIKE PEPTIDE 1 (9-36) AMIDE (HUMAN, BOVINE, GUINEA PIG, MOUSE, PORCINE, RAT)
GLU-GLY-THR-PHE-THR-SER-ASP-VAL-SER-SER-TYR-LEU-GLU-GLY-GLN-ALA-ALA-LYS-GLU-PHE-ILE-ALA-TRP-LEU-VAL-LYS-GLY-ARG-NH2
H-GLU-GLY-THR-PHE-THR-SER-ASP-VAL-SER-SER-TYR-LEU-GLU-GLY-GLN-ALA-ALA-LYS-GLU-PHE-ILE-ALA-TRP-LEU-VAL-LYS-GLY-ARG-NH2
Proglucagon (80-107) aMide (huMan, bovine, guinea pig, Mouse, porcine, rat), Preproglucagon (100-127) aMide (huMan, bovine, guinea pig, Mouse, porcine, rat), Glucagon-Like Peptide 1 (9-36) aMide (huMan, bovine, guinea pig, Mouse, porcine, rat)
GLP-1 (9-36) aMide (huMan, bovine, guinea pig, Mouse, porcine, rat)
Proglucagon (80-107) aMide (huMan, bovine, guinea pig, Mouse, porcine, rat), Preproglucagon (100-127) aMide (huMan, bovine, guinea pig, Mouse, porcine, rat), Glucagon-Like Peptide 1 (9-36
L-Argininamide, L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-lysylglycyl- | [Molecular Formula]
C140H214N36O43 | [MDL Number]
MFCD08458607 | [MOL File]
161748-29-4.mol | [Molecular Weight]
3089.41 |
| Chemical Properties | Back Directory | [density ]
1.46±0.1 g/cm3(Predicted) | [storage temp. ]
Desiccate at -20°C | [solubility ]
Soluble to 2 mg/ml in 0.025% acetic acid | [form ]
Powder | [color ]
White to off-white | [Sequence]
Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2 |
| Hazard Information | Back Directory | [Uses]
GLP-1(9-36)amide is a major metabolite of glucagon-like peptide-1-(7-36) amide formed by the enzyme dipeptidyl peptidase-4 (DPP-4). GLP-1(9-36)amide acts as an antagonist to the human pancreatic GLP-1 receptor[1][2]. | [storage]
-20°C | [References]
[1] Knudsen LB, et al. Glucagon-like peptide-1-(9-36) amide is a major metabolite of glucagon-like peptide-1-(7-36) amide after in vivo administration to dogs, and it acts as an antagonist on the pancreatic receptor. Eur J Pharmacol. 1996;318(2-3):429-435. DOI:10.1016/s0014-2999(96)00795-9
[2] Elahi D, et al. GLP-1 (9-36) amide, cleavage product of GLP-1 (7-36) amide, is a glucoregulatory peptide. Obesity (Silver Spring). 2008;16(7):1501-1509. DOI:10.1038/oby.2008.229 |
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