| Identification | Back Directory | [Name]
N-(S-acetylmercaptoacetyl)-4-isothiocyanate-phenylalanyl-glycyl-glycine ethyl ester | [CAS]
161876-61-5 | [Synonyms]
N-(S-acetylmercaptoacetyl)-4-isothiocyanate-phenylalanyl-glycyl-glycine ethyl ester
Glycine, (acetylthio)acetyl-4-isothiocyanato-L-phenylalanylglycyl-, ethyl ester (9CI) | [Molecular Formula]
C20H24N4O6S2 | [MOL File]
161876-61-5.mol | [Molecular Weight]
480.56 |
| Hazard Information | Back Directory | [Uses]
MAIPGG is a bifunctional chelator and an intermediate in the synthesis of radionuclide drug conjugates (RDCs). MAIPGG can be for the radiolabeling of a variety of monoclonal antibodies with 99mTc or 186Re, which then can be used for radioimmunodetection and radioimmunotherapy of cancer[1]. | [References]
[1] Ram S, et al. A peptide-based bifunctional chelating agent for 99mTc- and 186Re-labeling of monoclonal antibodies. Cancer. 1994 Feb 1;73(3 Suppl):769-73. DOI:10.1002/1097-0142(19940201)73:3+<769::aid-cncr2820731304>3.0.co;2-a |
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