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1619-29-0

1619-29-0 Structure

1619-29-0 Structure
IdentificationBack Directory
[Name]

helminthosporol
[CAS]

1619-29-0
[Synonyms]

helminthosporol
(1R,5S,8-anti)-8-Hydroxymethyl-1,7-dimethyl-4α-isopropylbicyclo[3.2.1]oct-6-ene-6-carbaldehyde
Bicyclo[3.2.1]oct-6-ene-6-carboxaldehyde, 8-(hydroxymethyl)-1,7-dimethyl-4-(1-methylethyl)-, (1R,4R,5S,8S)-
[Molecular Formula]

C15H24O2
[MOL File]

1619-29-0.mol
[Molecular Weight]

236.35
Chemical PropertiesBack Directory
[Melting point ]

98°
[alpha ]

D23 -28.7° (c = 1.93 in CHCl3)
[EPA Substance Registry System]

Bicyclo[3.2.1]oct-6-ene-6-carboxaldehyde, 8-(hydroxymethyl)-1,7-dimethyl-4-(1-methylethyl)-, (1R,4R,5S,8S)- (1619-29-0)
Hazard InformationBack Directory
[Uses]

Helminthosporol is a natural plant growth-regulator that can promote the growth of rice and lettuce seedlings. Helminthosporol can also inhibit the activity of acyl-CoA: cholesterol acyltransferase (ACAT) in rat liver microsomes and the synthesis of cholesterol esters in macrophages[1][2][3].
[References]

[1] Li YY, et al. Bioactive seco-Sativene Sesquiterpenoids from an Artemisia desertorum Endophytic Fungus, Cochliobolus sativus. J Nat Prod. 2020 May 22;83(5):1488-1494. DOI:10.1021/acs.jnatprod.9b01148
[2] Tamura S, et al. Isolation of helminthosporol as a natural plant growth-regulator and its chemical structure. Agricultural and Biological Chemistry, 1965, 29(3): 216-221.
[3] PARK J K O O, et al. Inhibition of acyl-CoA: cholesterol acyltransferase by helminthosporol and its related compounds. The Journal of Antibiotics, 1993, 46(8): 1303-1305.
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