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1619269-19-0

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1619269-19-0 Structure

1619269-19-0 Structure
IdentificationBack Directory
[Name]

[1,1'-Biphenyl]-3,4-diol, 4'-[4-[2-[[(6R)-2-amino-4,5,6,7-tetrahydro-6-benzothiazolyl]propylamino]ethyl]-1-piperazinyl]-
[CAS]

1619269-19-0
[Synonyms]

Tau-aggregation-IN-1
[1,1'-Biphenyl]-3,4-diol, 4'-[4-[2-[[(6R)-2-amino-4,5,6,7-tetrahydro-6-benzothiazolyl]propylamino]ethyl]-1-piperazinyl]-
[Molecular Formula]

C28H37N5O2S
[MOL File]

1619269-19-0.mol
[Molecular Weight]

507.7
Chemical PropertiesBack Directory
[Boiling point ]

740.2±60.0 °C(Predicted)
[density ]

1.32±0.1 g/cm3(Predicted)
[pka]

9.90±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

Tau-aggregation-IN-1 (Compound D-519) is a tau441 protein aggregation inhibitor with an IC50 of 21 μM. Tau-aggregation-IN-1 is also a dopamine D2 and D3 receptor agonist[1].
[IC 50]

D2 Receptor; D3 Receptor
[References]

[1] Iva Ziu, et al. The multifunctional dopamine D2/D3 receptor agonists also possess inhibitory activity against the full-length tau441 protein aggregation. Bioorg Med Chem. 2020 Sep 15;28(18):115667. DOI:10.1016/j.bmc.2020.115667
1619269-19-0 suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +17819995354 , +17819995354
Website:
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
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