| Identification | Back Directory | [Name]
Myostatin inhibitory peptide 7 | [CAS]
1621169-52-5 | [Synonyms]
Myostatin inhibitory peptide 7
ACE-031Myostatininhibitorypeptide7 | [Molecular Formula]
C133H227N43O33 | [MOL File]
1621169-52-5.mol | [Molecular Weight]
2956.49 |
| Chemical Properties | Back Directory | [density ]
1.44±0.1 g/cm3(Predicted) | [form ]
Solid | [color ]
White to off-white | [Sequence]
Ala-Trp-Arg-Gln-Asn-Thr-Arg-Tyr-Ser-Arg-Ile-Glu-Ala-Ile-Lys-Ile-Gln-Ile-Leu-Ser-Lys-Leu-Arg-Leu-NH2 | [InChIKey]
HXWLNPUQPASIHW-OOXKGWPCSA-N |
| Hazard Information | Back Directory | [Uses]
Myostatin inhibitory peptide 2 (compd 2) is a myostatin inhibitor with a Kd of 35.9 nM. Myostatin inhibitory peptide 2 can be used for researches of muscle atrophic disorders[1]. | [in vivo]
Myostatin inhibitory peptide 2 (0.75 mM, 40 μL, i.m., once every two weeks for 4 weeks) increases the muscle weight of skeletal muscles in muscular dystrophy model mice[1].
| [References]
[1] Takayama K, et al. Identification of the minimum peptide from mouse myostatin prodomain for human myostatin inhibition. J Med Chem. 2015 Feb 12;58(3):1544-9. DOI:10.1021/jm501170d |
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