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1621326-32-6

1621326-32-6 Structure

1621326-32-6 Structure
IdentificationBack Directory
[Name]

(S)-4'-nitro-Blebbistatin
[CAS]

1621326-32-6
[Synonyms]

para-Nitroblebbistatin
(S)-4'-nitro-Blebbistatin
(3aS)-1,2,3,3a-tetrahydro-3a-hydroxy-6-methyl-1-(4-nitrophenyl)-4H-pyrrolo[2,3-b]quinolin-4-one
4H-Pyrrolo[2,3-b]quinolin-4-one, 1,2,3,3a-tetrahydro-3a-hydroxy-6-methyl-1-(4-nitrophenyl)-, (3aS)-
[Molecular Formula]

C18H15N3O4
[MDL Number]

MFCD32062796
[MOL File]

1621326-32-6.mol
[Molecular Weight]

337.33
Chemical PropertiesBack Directory
[Boiling point ]

578.7±60.0 °C(Predicted)
[density ]

1.47±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMF: 20 mg/ml,DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml,DMSO: 12.5 mg/ml
[form ]

A crystalline solid
[pka]

10.88±0.20(Predicted)
[color ]

Yellow to orange
Hazard InformationBack Directory
[Uses]

para-Nitroblebbistatin is a non-cytotoxic, photostable, fluorescent and specific Myosin II inhibitor, usd in the study of the specific role of myosin II in physiological, developmental, and cell biological studies[1].
[References]

[1] Képiró M, et al. para-Nitroblebbistatin, the non-cytotoxic and photostable myosin?II inhibitor. Angew Chem Int Ed Engl. 2014 Jul 28;53(31):8211-5. DOI:10.1002/anie.201403540
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