| Identification | Back Directory | [Name]
CP-220629 | [CAS]
162141-96-0 | [Synonyms]
CP-220629
UNII-BAV9N49AFE
7H-Pyrazolo[3,4-c]pyridin-7-one, 1-cyclopentyl-3-ethyl-1,4,5,6-tetrahydro-6-(2-methylphenyl)- | [Molecular Formula]
C20H25N3O | [MOL File]
162141-96-0.mol | [Molecular Weight]
323.43 |
| Hazard Information | Back Directory | [Uses]
CP-220629 is a potent inhibitor of PDE4, with the IC50 of 0.44 μM. CP-220629 is efficacious in the guinea pig aerosolized antigen induced airway obstruction assay (ED50 2.0 mg/kg)[1]. | [IC 50]
PDE4: 0.44 μM (IC50) | [References]
[1] A J Duplantier, et al. 7-Oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridines as novel inhibitors of human eosinophil phosphodiesterase. J Med Chem. 1998 Jun 18;41(13):2268-77. DOI:10.1021/jm9800090 |
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