| Identification | Back Directory | [Name]
BRCA1-IN-1 | [CAS]
1622262-74-1 | [Synonyms]
BRCA1-IN-1
BRCA1 IN 1,BRCA-1-IN-1,BRCA1IN1
Phosphonic acid, P-[(3S)-1,1-difluoro-3-[[3-(1H-indol-3-yl)-1-oxopropyl]amino]-4-oxo-4-[[2-oxo-2-[(4-phenylbutyl)amino]ethyl]amino]butyl]- | [Molecular Formula]
C27H33F2N4O6P | [MDL Number]
MFCD30747868 | [MOL File]
1622262-74-1.mol | [Molecular Weight]
578.54 |
| Hazard Information | Back Directory | [Uses]
BRCA1-IN-1 is a novel small-molecule-like BRCA1 inhibitor with IC50 and Ki of 0.53 μM and 0.71 μM, respecrively. | [References]
[1] Na Z, et al. Discovery of cell-permeable inhibitors that target the BRCT domain of BRCA1 protein by using a small-molecule microarray. Angew Chem Int Ed Engl. 2014 Aug 4;53(32):8421-6. DOI:10.1002/anie.201405169 |
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| Company Name: |
BOC Sciences
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| Tel: |
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| Website: |
https://www.bocsci.com |
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