| Identification | Back Directory | [Name]
Pyrimido[2,1-c][1,4]oxazin-4(9H)-one, 6-(2,2-dimethylpropyl)-6,7-dihydro-2-(2-pyridinylmethoxy)-, (6R)- | [CAS]
1622291-66-0 | [Synonyms]
PF6462894
PF-6462894
PF 6462894
PF06462894,PF 06462894
Pyrimido[2,1-c][1,4]oxazin-4(9H)-one, 6-(2,2-dimethylpropyl)-6,7-dihydro-2-(2-pyridinylmethoxy)-, (6R)- | [Molecular Formula]
C18H23N3O3 | [MOL File]
1622291-66-0.mol | [Molecular Weight]
329.39 |
| Chemical Properties | Back Directory | [Boiling point ]
487.1±55.0 °C(Predicted) | [density ]
1.21±0.1 g/cm3(Predicted) | [storage temp. ]
room temp | [solubility ]
DMSO: 5mg/mL, clear (warmed) | [form ]
powder | [pka]
4.41±0.12(Predicted) | [color ]
white to beige |
| Hazard Information | Back Directory | [Uses]
(R)-6-Neopentyl-2-(pyridin-2-ylmethoxy)-6,7-dihydropyrimido[2,1-c][1,4]oxazin-4(9H)-one is a mGluR5 modulator. Also used in mGluR5 modulators screening studies. | [Biological Activity]
PF-06462894 is a muscarinic metabotropic receptor mGluR5 ligand. |
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| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
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