| Chemical Properties | Back Directory | [Boiling point ]
609.2±65.0 °C(Predicted) | [density ]
1.29±0.1 g/cm3(Predicted) | [solubility ]
DMF: 10 mg/ml
DMSO: 10 mg/ml
Ethanol: 10 mg/ml | [form ]
Solid | [pka]
3.20±0.27(Predicted) | [color ]
Off-white to light yellow | [InChI]
InChI=1S/C23H25N7O2/c1-14(2)27-23-25-12-18(22(31)30(23)5)19-6-7-21(15(3)28-19)32-17-8-9-24-20(10-17)16-11-26-29(4)13-16/h6-14H,1-5H3,(H,25,27) | [InChIKey]
TVGAHWWPABTBCX-UHFFFAOYSA-N | [SMILES]
C1(NC(C)C)=NC=C(C2=NC(C)=C(OC3C=CN=C(C4=CN(C)N=C4)C=3)C=C2)C(=O)N1C |
| Hazard Information | Back Directory | [Uses]
Vimseltinib (DCC-3014) is a c-FMS (CSF-IR) and c-Kit dual inhibitor extracted from patent WO2014145025A2, Compound Example 10, has IC50s of <0.01 μM and 0.1-1 μM, respectively[1]. | [References]
[1] Yumi Ahn, et al. 2-aminopyrimidin-6-ones and analogs exhibiting anti-cancer and anti-proliferative activities. WO2014145025A2. |
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