| Identification | Back Directory | [Name]
(S)-3,5-DIHYDROXYPHENYLGLYCINE | [CAS]
162870-29-3 | [Synonyms]
S-DHPG
(S)-3,5-DHPG
(S)-3,5-DIHYDROXYPHENYLGLYCINE
(S)-3,5-Dihydroxylphenylglycine
(S)-3,5-Dihydroxyphenylglycine hydrate
+-2,5-DIMETHOXY-4-IODOAMPHETAMINE HYDROCHLORIDE
Benzeneacetic acid, α-amino-3,5-dihydroxy-, (αS)- | [EINECS(EC#)]
2017-001-1 | [Molecular Formula]
C8H9NO4 | [MDL Number]
MFCD00673763 | [MOL File]
162870-29-3.mol | [Molecular Weight]
183.16 |
| Chemical Properties | Back Directory | [Melting point ]
>207°C (dec.) | [Boiling point ]
448.8±33.0 °C(Predicted) | [density ]
1.550±0.06 g/cm3(Predicted) | [storage temp. ]
−20°C
| [solubility ]
Aqueous Base (Very Slightly, Sonicated), Methanol (Slightly), Water (Slightly, Heated) | [form ]
solid
| [pka]
1.77±0.10(Predicted) | [color ]
white
| [Water Solubility ]
Soluble to 50 mM in water | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Uses]
(S)-3,5-Dihydroxylphenylglycine is a potent agonist of group I metabotropic glutamate receptors mGluR1 and mGluR5. (S)-3,5-Dihydroxylphenylglycine have been utilized for the treatment of neuronal inju
ry and cognitive enhancement. | [Definition]
ChEBI: (S)-3,5-dihydroxyphenylglycine is a glycine derivative that is L-alpha-phenylglycine substituted at positions 3 and 5 on the phenyl ring by hydroxy groups. It is a member of resorcinols and a non-proteinogenic L-alpha-amino acid. It is functionally related to a L-alpha-phenylglycine. It is a tautomer of a (S)-3,5-dihydroxyphenylglycine zwitterion. | [Biological Activity]
Selective group I mGlu receptor agonist. Also available as part of the Group I mGlu Receptor Tocriset™ and Mixed mGlu Receptor Tocriset™ . | [Biochem/physiol Actions]
(S)-3,5-Dihydroxyphenylglycine hydrate is a group I metabotropic glutamate receptor agonist. | [storage]
-20°C (desiccate). Protect from light. |
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