| Identification | Back Directory | [Name]
NSC 756093 | [CAS]
1629908-92-4 | [Synonyms]
NSC 756093
NSC756093 >=98% (HPLC)
4-(2-hydroxyethyl)-6-methoxy-9-phenyl-3,9-dihydrofuro[3,4-b]quinolin-1-one
paclitaxel resistant,anticancer,NSC756093,ovarian cancer,NCI-60 cell,inhibit,SKOV3 cells,Inhibitor | [Molecular Formula]
C20H19NO4 | [MDL Number]
MFCD28902215 | [MOL File]
1629908-92-4.mol | [Molecular Weight]
337.37 |
| Chemical Properties | Back Directory | [Boiling point ]
561.8±50.0 °C(Predicted) | [density ]
1.35±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
DMSO: soluble | [form ]
A solid | [pka]
14.56±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
NSC756093 is the first inhibitor of the GBP1 and PIM1 interaction. | [Biological Activity]
NSC756093a podophyllotoxin analogis a potent and specific inhibitor of GBP1:PIM1 interaction th at inhibits proliferation of paclitaxel resistant cancer cells. ApparentlyNSC756093 stabilizes a conformation of GBP1 not suitable for binding to PIM1. |
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| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
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| Tel: |
4008-099-669 |
| Website: |
https://www.chemicalbook.com/ShowSupplierProductsList112975/0.htm |
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