| Identification | Back Directory | [Name]
Nebostinel | [CAS]
163000-63-3 | [Synonyms]
XY2401 XY-2401 XY 2401 Nebostinel Befiradol Fumarate Pentanoic acid, 4-amino-5-[(4,4-dimethylcyclohexyl)amino]-5-oxo-, (4S)- | [Molecular Formula]
C13H24N2O3 | [MDL Number]
MFCD00932765 | [MOL File]
163000-63-3.mol | [Molecular Weight]
256.34 |
| Hazard Information | Back Directory | [Uses]
Neboglamine (CR-2249; XY-2401) is a modulator for N-methyl-D-aspartate (NMDA) receptor. Neboglamine increases the levels of fos-like immunoreactivity (FLI)-positive cells in the prefrontal cortex, nucleus accumbens, and lateral septal nucleus in rat models, .restores NMDA (HY-17551) -mediated neurotransmitter release, and inhibits phencyclidine-induced hyperlocomotion[1]. | [References]
[1] Chiusaroli R, et al., Antipsychotic-like effects of the N-methyl-D-aspartate receptor modulator neboglamine: an immunohistochemical and behavioural study in the rat. Pharmacol Res. 2010 May;61(5):430-6. DOI:10.1016/j.phrs.2009.12.010 |
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