| Hazard Information | Back Directory | [Uses]
Ranevetmab (NV-01) is a caninised anti-NGF monoclonal antibody (mAb). Ranevetmab can alleviate pain, and is used for the research of degenerative joint disease (DJD) pain[1]. | [in vivo]
Ranevetmab (200 μg/kg, i.v.) alleviates degenerative joint disease (DJD) pain in dogs[1].
| Animal Model: | Dogs with degenerative joint disease (DJD) pain[2] | | Dosage: | 200 μg/kg | | Administration: | i.v. | | Result: | Improved canine brief pain inventory (CBPI), pain severity (PS) and pain interference (PI) scores. |
| [IC 50]
NGF | [References]
[1] Lascelles BD, et al. A canine-specific anti-nerve growth factor antibody alleviates pain and improves mobility and function in dogs with degenerative joint disease-associated pain. BMC Vet Res. 2015 Apr 30;11:101. DOI:10.1186/s12917-015-0413-x |
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Biolab Reagents
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Cell Sciences
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www.cellsciences.com |
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