1636878-36-8

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1636878-36-8 Structure

Chemical Properties	Back Directory
[Melting point ] 206-208 °C
[Boiling point ] 737.8±60.0 °C(predicted)
[density ] 1.24±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[pka] 13.52±0.70(predicted)

Hazard Information	Back Directory
[Uses] MBX3135 is an efflux pump inhibitor which can enhance the effect of antibiotics through the AcrB target of bacteria. MBX3135 can be used for research of infection and antibiotics[1].
[References] [1] Sjuts H, et al. Molecular basis for inhibition of AcrB multidrug efflux pump by novel and powerful pyranopyridine derivatives. Proc Natl Acad Sci U S A. 2016 Mar 29;113(13):3509-14. DOI:10.1073/pnas.1602472113

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