| Identification | Back Directory | [Name]
L-Aspartic acid, L-cysteinylglycylglycylglycyl-L-prolyl-L-lysyl-L-lysyl-L-lysyl-L-arginyl-L-lysyl-L-valyl-L-α-glutamyl- | [CAS]
163815-24-5 | [Synonyms]
L-Aspartic acid, L-cysteinylglycylglycylglycyl-L-prolyl-L-lysyl-L-lysyl-L-lysyl-L-arginyl-L-lysyl-L-valyl-L-α-glutamyl- | [Molecular Formula]
C58H104N20O18S | [MOL File]
163815-24-5.mol | [Molecular Weight]
1401.63 |
| Chemical Properties | Back Directory | [density ]
1.50±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
2.82±0.10(Predicted) | [color ]
White to off-white | [Sequence]
Cys-Gly-Gly-Gly-Pro-Lys-Lys-Lys-Arg-Lys-Val-Glu-Asp |
| Hazard Information | Back Directory | [Uses]
SV40 large T antigen NLS is from Large T antigen residue 47 to 55, enables protein import into cell nucleus. | [References]
[1] Xiao CY, et al. Negative charge at the protein kinase CK2 site enhances recognition of the SV40 large T-antigen NLS by importin: effect of conformation. FEBS Lett. 1998 Dec 4;440(3):297-301. DOI:10.1016/s0014-5793(98)01478-1
[2] Xiao CY, et al. An engineered site for protein kinase C flanking the SV40 large T-antigen NLS confers phorbol ester-inducible nuclear import. FEBS Lett. 1998 Oct 9;436(3):313-7. DOI:10.1016/s0014-5793(98)01157-0 |
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