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1638632-09-3

1638632-09-3 Structure

1638632-09-3 Structure
IdentificationBack Directory
[Name]

L-Cysteinyl-L-cysteinyl-L-α-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-asparaginyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonylglycyl-L-cysteinyl-L-Tyrosine Trifluoroacetate
[CAS]

1638632-09-3
[Synonyms]

Linaclotide-line
Linaclotide Linear Trifluoroacetate
Linaclotide Impurity 3 (Linaclotide Linear Trifluoroacetate)
L-Cysteinyl-L-cysteinyl-L-α-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-asparaginyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonylglycyl-L-cysteinyl-L-Tyrosine Trifluoroacetate
L-?Cysteinyl-?L-?cysteinyl-?L-?α-?glutamyl-?L-?tyrosyl-?L-?cysteinyl-?L-?cysteinyl-?L-?asparaginyl-?L-?prolyl-?L-?alanyl-?L-?cysteinyl-?L-?threonylglycyl-?L-?cysteinyl-L-?Tyrosine Trifluoroacetate
[Molecular Formula]

C61H86F3N15O23S6
[MOL File]

1638632-09-3.mol
[Molecular Weight]

1646.8
Chemical PropertiesBack Directory
[Melting point ]

>192°C (dec.)
[storage temp. ]

-20°C Freezer, Under inert atmosphere
[solubility ]

DMSO (Slightly), Methanol (Slightly), Water (Very Slightly)
[form ]

Solid
[color ]

White to Off-White
Hazard InformationBack Directory
[Uses]

L-?Cysteinyl-?L-?cysteinyl-?L-?α-?glutamyl-?L-?tyrosyl-?L-?cysteinyl-?L-?cysteinyl-?L-?asparaginyl-?L-?prolyl-?L-?alanyl-?L-?cysteinyl-?L-?threonylglycyl-?L-?cysteinyl-L-?Tyrosine is a derivative of Linaclotide (L465880), a guanylate cyclase-C agonist currently being studied in Phase 3 trials for the treatment of irritable bowel syndrome with constipation.
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