| Identification | Back Directory | [Name]
Valbenazine tosylate | [CAS]
1639208-54-0 | [Synonyms]
NBI-98854 Tosylate
Valbenazine tosylate
Valbenazine Ditosylate | [Molecular Formula]
C31H46N2O7S | [MDL Number]
MFCD32696930 | [MOL File]
1639208-54-0.mol | [Molecular Weight]
590.78 |
| Hazard Information | Back Directory | [Uses]
Valbenazine tosylate (NBI-98854 tosylate) is a vesicular monoamine transporter 2 (VMAT2) inhibitor with the Ki of 110-190 nM[1]. | [in vivo]
Valbenazine (10 mg/kg; orally) induces ptosis (primarily an adrenergic response) and increases plasma prolactin primarily a dopaminergic response in rats[1]. | [storage]
Store at -20°C | [References]
[1] Dimitri E Grigoriadis, et al. Pharmacologic Characterization of Valbenazine (NBI-98854) and Its Metabolites. J Pharmacol Exp Ther. 2017 Jun;361(3):454-461. DOI:10.1124/jpet.116.239160 |
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