| Identification | Back Directory | [Name]
thalicminine | [CAS]
16408-77-8 | [Synonyms]
thalicminine
4,10,11-Trimethoxy-8H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinolin-8-one
8H-Benzo[g]-1,3-benzodioxolo[6,5,4-de]quinolin-8-one, 4,10,11-trimethoxy- | [Molecular Formula]
C20H15NO6 | [MDL Number]
MFCD27989250 | [MOL File]
16408-77-8.mol | [Molecular Weight]
365.34 |
| Hazard Information | Back Directory | [Description]
The roots of Thalictrum minus contain this 10-oxoaporphine alkaloid which
contains three methoxyl groups, a methylenedioxy group and a conjugated keto
group. Prolonged reduction with Zn dust in AcOH-H2S04 gives the hexahydro
derivative, m.p. 180-2°C which has an ultraviolet spectrum in EtOH showing
absorption maxima at 218,280 and 302 II1J1. The alkaloid is formed by the
oxidation of Thalicmine (q.v.) with KMn04 in Me2CO or chromic acid in
pyridine. | [Uses]
Thalicminine is an alkaloid, which is found in Thalictrum species. Thalicminine can cause respiratory stimulation and a brief hypotensive effect on dogs. Thalicminine also prolongs the hypnotic effect of Chloral hydrate in mice[1]. | [References]
Pulatova, Ismailov, Yunusov., Khim. Prir. Soedin, 2, 426 (1966) |
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